About me
I am a research group leader of the Vascular Surgery Research Group, Södersjukhuset. We conduct projects in the field of vascular diseases. The group is presented on a web page at the Institution of Clinical Science and Education, Södersjukhuset - SOSVASC. The research has a strong clinical focus including evaluating the results of both established and new therapies as well as basic science. Much of the clinical research is associated with arteriosclerosis and degenerative vascular disease. The Vascular Section of Surgery, Södersjukhuset, is the second largest clinic in the country and we annually get requests for participation in scientific multicenter studies, both in terms of method development and new treatment. In my role as a research groupleader I focuse on the ongoing PhD projects, my own projects and the multicenter trials we conduct. My main task at Karolinska Institutet, is thus to support the members of the research team, as well as helping them to create the conditions for conducting research. My own research career began with the study of malignant melanoma (PhD2002) but my focus is now on the ongoing vascular projects.
Research description
Ongoing projects:
Infammatory markers predisposing for arteriosclerosis.
How fast should we operate patients with symptomatic carotis stenosis.
Cellular and molecular bitmarkers for unstable plaque in carotid stenosis.
Natural history for patients with periferal arterial diesease.
Long term follow up after primary subclavian vein trombosis.
Seven selected publications
- Mortality with Paclitaxel-Coated Devices in Peripheral Artery Disease.
- Nordanstig J, James S, Andersson M, Andersson M, Danielsson P, Gillgren P, Delle M, Engström J, Fransson T, Hamoud M, Hilbertson A, Johansson P, Karlsson L, Kragsterman B, Lindgren H, Ludwigs K, Mellander S, Nyman N, Renlund H, Sigvant B, Skoog P, Starck J, Tegler G, Toivola A, Truedson M, Wahlgren CM, Wallinder J, Öjersjö A, Falkenberg M.Nordanstig J, et al. N Engl J Med. 2020 Dec 24;383(26):2538-2546. doi: 10.1056/NEJMoa2005206. Epub 2020 Dec 9
2-cm versus 4-cm excision margins for primary cutaneous melanoma thicker than 2 mm: a randomized, multicentre trial. Gillgren P, Drzewiecki KT, Niin M, Gullestad, HP, Hellborg H, Mansson-Brahme, E, Ingvar C, Call Borg U. Lancet. 2011 Nov 5; 378 (9803): 1635-42.
Peri-procedural risk with the Urgent Carotid Artery Stenting: A Population-based Study Swedvasc. Jonsson M, Gillgren P, Wanhainen A, Acosta S, Lindstrom D. Eur J Vasc Endovasc Surg. 2015 February 28. PII: S1078-5884 (15) 00045-3. doi: 10.1016/j.ejvs.2015.01.007.
Outcome After Seven Years of carotid artery stenting and endarectomi in Sweden - single center and the national results. Lindstrom D, Jonsson M, Formgren J, Delle M, Rosfors S, Gillgren P. Eur J Vasc Endovasc Surg. 2012 May;43(5):499-503.
Profiling of atherosclerotic lesions by Gene and tissue microarrays Reveals PCSK6 as a novel protease in unstable carotid atherosclerosis. Perisic L, Hedin E, Razuvaev A, Lengquist M, Osterholm C, Folkersen L, Gillgren P , Paulsson-Berne G, Ponten F, Odeberg J, Hedin U. Arterioscler Thromb Vasc Biol. 2013 Oct;33(10):2432-43.
Sentinel node location in trunk and extremity melanomas: uncommon or multiple lymph drainage does not affect survival. Gordon D, Smedby KE, Schultz I, Olsson H, Ingvar C, Hansson J, Gillgren P . Ann Surg Oncol. 2014 Oct;21(11):3386-94.
The role of procalcitonin in postimplantation syndrome after EVAR: a pilot study. The role of procalcitonin in postimplantation syndrome after EVAR: a pilot study. Sartipy F, Lindström D, Gillgren P , Ternhag A. Ann Vasc Surg. 2014 May;28(4):866-73.