About me
Current positions
- Assistant professor, Karolinska Institutet
- Physician, Department of Endocrinology, Karolinska University Hospital
- Affiliated researcher, University of Tokyo
Education and previous positions
- Docent in epidemiology, Karolinska Institutet, 2020
- Intern physician (AT-läkare), Södersjukhuset & postdoc, Karolinska Institutet, 2017-2020
- Post-doctoral researcher, Harvard University, 2014-2016
- PhD, Karolinska Institutet, 2014
- BSc, Stockholm School of Economics (Handelshögskolan), 2012
- MD, Karolinska Institutet, 2012
Research description
We address research questions of relevance to public health and clinical decision making, with a main clinical interest in internal medicine and endocrinology. We use methods for causal inference, simulations, and risk prediction modelling in observational and interventional study designs.
Main research areas include:
Safety and effectiveness of glucose-lowering drugs
We use nationwide data sources from three countries to emulate clinical trials in observational data (Björn Pasternak Group) Focus on treatment for type 2 diabetes, including SGLT2 inhibitors and GLP-1 receptor agonists.
Cardiovascular risk prediction and pharmacological prevention of cardiovascular disease
We assess research questions related to primary and secondary prevention of cardiovascular disease, including validation of risk scores and assessment of guideline-recommended treatment algorithms. Focus on antiplatelet therapy and cholesterol-lowering drugs.
Emerging issues in sexual health and fertility
Research program in collaboration with the University of Tokyo, with focus on young Japanese adults. Studies on the epidemiology of sexual activity and novel topics in sexual health research using data from national probability surveys. Some comments are presented here.
PhD-students
Main supervisor for:
- Arvid Engström, MD
- Kinda Malki, MD
Co-supervisor for:
- Ali Yari, MD
- Moa Simonsson, MD
Research students
- Carl-Emil Lim, medical student
- Cyrus Ghaznavi, medical student
Our research is and has been funded by:
- Swedish Heart-Lung Foundation
- Swedish Diabetes Foundation
- Swedish Society for Medical Research
- Karolinska Institutet Foundations and Funds
- Faculty-funded career position, Karolinska Institutet
Publications
Selected publications
Sakamoto H, Ishikane M, Ueda P. Seasonal Influenza Activity during the SARS-CoV-2 Outbreak in Japan. JAMA 2020.
Pasternak B, Wintzell V, Melbye M, Eliasson B, Svensson AM, Franzen S, Gubjörnsdottir S, Hveem K, Jonasson C, Svanström H, Ueda P Use of sodium-glucose co-transporter 2 inhibitors and risk of serious renal events: Scandinavian cohort study. BMJ 2020
Allahyari A, Jernberg T, Hagström E, Leosdottir M, Lundman P, Ueda P. Application of the 2019 ESC/EAS dyslipidaemia guidelines to nationwide data of patients with a recent myocardial infarction: a simulation study Eur Heart J 2020
Pasternak B, Ueda P, Eliasson B, Svensson AM, Franzen S, Gubjörnsdottir S, Hveem K, Jonasson C, Wintzell V, Melbye M, Svanström H. Use of sodium glucose cotransporter 2 inhibitors and risk of major cardiovascular events and heart failure: Scandinavian register based cohort study. BMJ 2019
Ueda P, Svanström H, Melbye M, Eliasson B, Svensson AM, Franzen S, Gubjörnsdottir S, Hveem K, Jonasson C, Pasternak B. Sodium glucose cotransporter 2 inhibitors and risk of serious adverse events: nationwide register based cohort study. BMJ 2018
Ueda P, Jernberg T, James S, Alfredsson J, Erlinge D, Omerovic E, Persson J, Ravn-Fischer A, Tornvall P, Svennblad B, Varenhorst C. External validation of the DAPT score in a nationwide population. J Am Coll Cardiol 2018
Ueda P, Jernberg T, Varenhorst C. Reply: The DAPT score in Sweden. Successful validation, flawed interpretation. J Am Coll Cardiol 2019
Svanström H, Ueda P, Melbye M, Eliasson B, Svensson AM, Franzen S, Gubjörnsdottir S, Hveem K, Jonasson C, Pasternak B. Use of liraglutide and risk of major cardiovascular events: a register-based cohort study in Denmark and Sweden. Lancet Diabetes & Endocrinology 2018
Howe BK*, Suharlim C*, Ueda P* (*Co-first authors), Howe D, Kawachi I, Rimm E. Gotta catch’em all! Pokémon GO and physical activity among young adults: difference in differences study. BMJ 2016
Coverage in The Guardian and Forbes
Ueda P, Woodward M, Lu Y, Hajifathalian K, et al. Laboratory-based and office-based risk scores and charts to predict 10-year risk of cardiovascular disease in 182 countries: a pooled analysis of prospective cohorts and health surveys. Lancet Diabetes & Endocrinology 2017
Ueda P, Lung T, Clarke P, Danaei, G. Application of the 2014 NICE cholesterol guidelines in the English population: a cross-sectional analysis. British Journal of General Practice 2017
Lu Y, Hajifathalian K, Ezzati M, Rimm E, Ueda P, Danaei G. Sick Population and Sick Subpopulations: Racial Disparities in Coronary Heart Disease Risk in the United States. Circulation 2016
Hajifathalian K*, Ueda P* (*Co-first authors), Lu Y, Woodward M, et al. Globorisk: A novel risk score for predicting cardiovascular disease risk in national populations: a pooled analysis of prospective cohorts and health examination surveys. Lancet Diabetes & Endocrinology 2015
Ueda P, Rafatnia F, Bäärnhielm M, Fröbom R, Korzunowicz G, Lönnebro R, Eyles D, Olsson T, Alfredsson L. Neonatal vitamin D and risk of multiple sclerosis. Annals of Neurology 2014
Hult M*, Tornhammar P*, Ueda P* (*Co-first authors), Chima C, Edstedt-Bonamy A-K, Ozumba B, Norman M. Hypertension, Diabetes and Overweight: Looming Legacies of the Biafran Famine. PLoS ONE 2010
Coverage in The New York Times