Petter Woll

About me
Publications
Public outreach and news

Research

Visit my web page at Petter Woll group [1]
[1] http://ki.se/en/medh/petter-woll-group

Articles

Article: BLOOD. 2024;143(11):953-966

Identification and surveillance of rare relapse-initiating stem cells during complete remission after transplantation.

Dimitriou M; Mortera-Blanco T; Tobiasson M; Mazzi S; Lehander M; Högstrand K; Karimi M; Walldin G; Jansson M; Vonlanthen S; Ljungman P; Langemeijer S; Yoshizato T; Hellström-Lindberg E; Woll PS; Jacobsen SEW
Article: CANCER RESEARCH. 2024;84(2):211-225

Erythroid Differentiation Enhances RNA Mis-Splicing in SF3B1-Mutant Myelodysplastic Syndromes with Ring Sideroblasts.

Moura PL; Mortera-Blanco T; Hofman IJ; Todisco G; Kretzschmar WW; Björklund A-C; Creignou M; Hagemann-Jensen M; Ziegenhain C; Cabrerizo Granados D; Barbosa I; Walldin G; Jansson M; Ashley N; Mead AJ; Lundin V; Dimitriou M; Yoshizato T; Woll PS; Ogawa S; Sandberg R; Jacobsen SEW; Hellström-Lindberg E
Article: BLOOD. 2023;142(19):1622-1632

Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells.

Matsuoka S; Facchini R; Luis TC; Carrelha J; Woll PS; Mizukami T; Wu B; Boukarabila H; Buono M; Norfo R; Arai F; Suda T; Mead AJ; Nerlov C; Jacobsen SEW
Article: BLOOD. 2023;142(17):1448-1462

Genome-wide transcription factor-binding maps reveal cell-specific changes in the regulatory architecture of human HSPCs.

Subramanian S; Thoms JAI; Huang Y; Cornejo-Páramo P; Koch FC; Jacquelin S; Shen S; Song E; Joshi S; Brownlee C; Woll PS; Chacon-Fajardo D; Beck D; Curtis DJ; Yehson K; Antonenas V; O'Brien T; Trickett A; Powell JA; Lewis ID; Pitson SM; Gandhi MK; Lane SW; Vafaee F; Wong ES; Göttgens B; Alinejad-Rokny H; Wong JWH; Pimanda JE
Article: CLINICAL CANCER RESEARCH. 2023;29(20):4256-4267

Integrated Genomic and Transcriptomic Analysis Improves Disease Classification and Risk Stratification of MDS with Ring Sideroblasts.

Todisco G; Creignou M; Bernard E; Björklund A-C; Moura PL; Tesi B; Mortera-Blanco T; Sander B; Jansson M; Walldin G; Barbosa I; Reinsbach SE; Hofman IJ; Nilsson C; Yoshizato T; Dimitriou M; Chang D; Olafsdottir S; Venckute Larsson S; Tobiasson M; Malcovati L; Woll P; Jacobsen SEW; Papaemmanuil E; Hellström-Lindberg E
Article: NATURE CANCER. 2023;4(10):1474-1490

A T cell receptor targeting a recurrent driver mutation in FLT3 mediates elimination of primary human acute myeloid leukemia in vivo.

Giannakopoulou E; Lehander M; Virding Culleton S; Yang W; Li Y; Karpanen T; Yoshizato T; Rustad EH; Nielsen MM; Bollineni RC; Tran TT; Delic-Sarac M; Gjerdingen TJ; Douvlataniotis K; Laos M; Ali M; Hillen A; Mazzi S; Chin DWL; Mehta A; Holm JS; Bentzen AK; Bill M; Griffioen M; Gedde-Dahl T; Lehmann S; Jacobsen SEW; Woll PS; Olweus J
Article: GENOME BIOLOGY. 2023;24(1):152

Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion.

Wojtowicz EE; Mistry JJ; Uzun V; Hellmich C; Scoones A; Chin DW; Kettyle LM; Grasso F; Lord AM; Wright DJ; Etherington GJ; Woll PS; Belderbos ME; Bowles KM; Nerlov C; Haerty W; Bystrykh LV; Jacobsen SEW; Rushworth SA; Macaulay IC
Article: NATURE BIOTECHNOLOGY. 2022;40(4):488-498

T cells targeted to TdT kill leukemic lymphoblasts while sparing normal lymphocytes.

Ali M; Giannakopoulou E; Li Y; Lehander M; Virding Culleton S; Yang W; Knetter C; Odabasi MC; Bollineni RC; Yang X; Foldvari Z; Böschen M-L; Taraldsrud E; Strønen E; Toebes M; Hillen A; Mazzi S; de Ru AH; Janssen GMC; Kolstad A; Tjønnfjord GE; Lie BA; Griffioen M; Lehmann S; Osnes LT; Buechner J; Garcia KC; Schumacher TN; van Veelen PA; Leisegang M; Jacobsen SEW; Woll P; Olweus J
Article: BLOOD. 2022;139(4):629-634

Aged healthy mice acquire clonal hematopoiesis mutations.

Chin DWL; Yoshizato T; Virding Culleton S; Grasso F; Barbachowska M; Ogawa S; Jacobsen SEW; Woll PS
Article: FRONTIERS IN IMMUNOLOGY. 2022;13:880668

FOXO Dictates Initiation of B Cell Development and Myeloid Restriction in Common Lymphoid Progenitors.

Peña-Pérez L; Kharazi S; Frengen N; Krstic A; Bouderlique T; Hauenstein J; He M; Somuncular E; Li Wang X; Dahlberg C; Gustafsson C; Johansson A-S; Walfridsson J; Kadri N; Woll P; Kierczak M; Qian H; Westerberg L; Luc S; Månsson R
Article: JOURNAL OF INTERNAL MEDICINE. 2021;289(5):650-661

Stem cell concepts in myelodysplastic syndromes: lessons and challenges.

Woll PS; Jacobsen SEW
Article: LEUKEMIA. 2020;34(1):271-282

A three-dimensional in vitro model of erythropoiesis recapitulates erythroid failure in myelodysplastic syndromes.

Elvarsdóttir EM; Mortera-Blanco T; Dimitriou M; Bouderlique T; Jansson M; Hofman IJF; Conte S; Karimi M; Sander B; Douagi I; Woll PS; Hellström-Lindberg E
Article: BLOOD. 2018;131(15):1712-1719

Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis.

Duarte S; Woll PS; Buza-Vidas N; Chin DWL; Boukarabila H; Luís TC; Stenson L; Bouriez-Jones T; Ferry H; Mead AJ; Atkinson D; Jin S; Clark S-A; Wu B; Repapi E; Gray N; Taylor S; Mutvei AP; Tsoi YL; Nerlov C; Lendahl U; Jacobsen SEW
Article: JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. 2018;22(4):2311-2318

Mapping the CLEC12A expression on myeloid progenitors in normal bone marrow; implications for understanding CLEC12A-related cancer stem cell biology.

Bill M; B van Kooten Niekerk P; S Woll P; Laine Herborg L; Stidsholt Roug A; Hokland P; Nederby L
Article: CELL STEM CELL. 2018;22(2):262-276.e7

In Vivo Labeling by CD73 Marks Multipotent Stromal Cells and Highlights Endothelial Heterogeneity in the Bone Marrow Niche.

Breitbach M; Kimura K; Luis TC; Fuegemann CJ; Woll PS; Hesse M; Facchini R; Rieck S; Jobin K; Reinhardt J; Ohneda O; Wenzel D; Geisen C; Kurts C; Kastenmüller W; Hölzel M; Jacobsen SEW; Fleischmann BK
Article: NATURE. 2018;554(7690):106-111

Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells.

Carrelha J; Meng Y; Kettyle LM; Luis TC; Norfo R; Alcolea V; Boukarabila H; Grasso F; Gambardella A; Grover A; Högstrand K; Lord AM; Sanjuan-Pla A; Woll PS; Nerlov C; Jacobsen SEW
Article: BLOOD. 2017;130(7):881-890

SF3B1-initiating mutations in MDS-RSs target lymphomyeloid hematopoietic stem cells.

Mortera-Blanco T; Dimitriou M; Woll PS; Karimi M; Elvarsdottir E; Conte S; Tobiasson M; Jansson M; Douagi I; Moarii M; Saft L; Papaemmanuil E; Jacobsen SEW; Hellström-Lindberg E
Article: CELL REPORTS. 2017;20(3):572-585

Integrative Genomics Identifies the Molecular Basis of Resistance to Azacitidine Therapy in Myelodysplastic Syndromes.

Unnikrishnan A; Papaemmanuil E; Beck D; Deshpande NP; Verma A; Kumari A; Woll PS; Richards LA; Knezevic K; Chandrakanthan V; Thoms JAI; Tursky ML; Huang Y; Ali Z; Olivier J; Galbraith S; Kulasekararaj AG; Tobiasson M; Karimi M; Pellagatti A; Wilson SR; Lindeman R; Young B; Ramakrishna R; Arthur C; Stark R; Crispin P; Curnow J; Warburton P; Roncolato F; Boultwood J; Lynch K; Jacobsen SEW; Mufti GJ; Hellstrom-Lindberg E; Wilkins MR; MacKenzie KL; Wong JWH; Campbell PJ; Pimanda JE
Article: JOURNAL OF EXPERIMENTAL MEDICINE. 2017;214(7):2005-2021

Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD-induced myeloproliferation.

Mead AJ; Neo WH; Barkas N; Matsuoka S; Giustacchini A; Facchini R; Thongjuea S; Jamieson L; Booth CAG; Fordham N; Di Genua C; Atkinson D; Chowdhury O; Repapi E; Gray N; Kharazi S; Clark S-A; Bouriez T; Woll P; Suda T; Nerlov C; Jacobsen SEW
Article: NATURE MEDICINE. 2017;23(6):692-702

Single-cell transcriptomics uncovers distinct molecular signatures of stem cells in chronic myeloid leukemia.

Giustacchini A; Thongjuea S; Barkas N; Woll PS; Povinelli BJ; Booth CAG; Sopp P; Norfo R; Rodriguez-Meira A; Ashley N; Jamieson L; Vyas P; Anderson K; Segerstolpe Å; Qian H; Olsson-Strömberg U; Mustjoki S; Sandberg R; Jacobsen SEW; Mead AJ
Article: HAEMATOLOGICA. 2017;102(3):498-508

Progression in patients with low- and intermediate-1-risk del(5q) myelodysplastic syndromes is predicted by a limited subset of mutations.

Scharenberg C; Giai V; Pellagatti A; Saft L; Dimitriou M; Jansson M; Jädersten M; Grandien A; Douagi I; Neuberg DS; LeBlanc K; Boultwood J; Karimi M; Jacobsen SEW; Woll PS; Hellström-Lindberg E
Article: NATURE IMMUNOLOGY. 2016;17(12):1424-1435

Initial seeding of the embryonic thymus by immune-restricted lympho-myeloid progenitors.

Luis TC; Luc S; Mizukami T; Boukarabila H; Thongjuea S; Woll PS; Azzoni E; Giustacchini A; Lutteropp M; Bouriez-Jones T; Vaidya H; Mead AJ; Atkinson D; Böiers C; Carrelha J; Macaulay IC; Patient R; Geissmann F; Nerlov C; Sandberg R; de Bruijn MFTR; Blackburn CC; Godin I; Jacobsen SEW
Article: ONCOTARGET. 2016;7(45):72685-72698

Perturbed hematopoietic stem and progenitor cell hierarchy in myelodysplastic syndromes patients with monosomy 7 as the sole cytogenetic abnormality.

Dimitriou M; Woll PS; Mortera-Blanco T; Karimi M; Wedge DC; Doolittle H; Douagi I; Papaemmanuil E; Jacobsen SEW; Hellström-Lindberg E
Article: BLOOD. 2016;128(2):217-226

Macrophage colony-stimulating factor receptor marks and regulates a fetal myeloid-primed B-cell progenitor in mice.

Zriwil A; Böiers C; Wittmann L; Green JCA; Woll PS; Jacobsen SEW; Sitnicka E
Article: NATURE IMMUNOLOGY. 2016;17(6):666-676

Distinct myeloid progenitor-differentiation pathways identified through single-cell RNA sequencing.

Drissen R; Buza-Vidas N; Woll P; Thongjuea S; Gambardella A; Giustacchini A; Mancini E; Zriwil A; Lutteropp M; Grover A; Mead A; Sitnicka E; Jacobsen SEW; Nerlov C
Article: CELL DEATH DISCOVERY. 2015;1:15008

Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia.

Watson AS; Riffelmacher T; Stranks A; Williams O; De Boer J; Cain K; MacFarlane M; McGouran J; Kessler B; Khandwala S; Chowdhury O; Puleston D; Phadwal K; Mortensen M; Ferguson D; Soilleux E; Woll P; Jacobsen SEW; Simon AK
Article: BRAIN STRUCTURE & FUNCTION. 2015;220(1):479-500

An animal model mimicking pedunculopontine nucleus cholinergic degeneration in Parkinson's disease.

Pienaar IS; Harrison IF; Elson JL; Bury A; Woll P; Simon AK; Dexter DT
Article: LEUKEMIA. 2015;29(1):38-50

Clonal variegation and dynamic competition of leukemia-initiating cells in infant acute lymphoblastic leukemia with MLL rearrangement.

Bardini M; Woll PS; Corral L; Luc S; Wittmann L; Ma Z; Lo Nigro L; Basso G; Biondi A; Cazzaniga G; Jacobsen SEW
Article: CANCER CELL. 2014;25(6):794-808

Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.

Woll PS; Kjällquist U; Chowdhury O; Doolittle H; Wedge DC; Thongjuea S; Erlandsson R; Ngara M; Anderson K; Deng Q; Mead AJ; Stenson L; Giustacchini A; Duarte S; Giannoulatou E; Taylor S; Karimi M; Scharenberg C; Mortera-Blanco T; Macaulay IC; Clark S-A; Dybedal I; Josefsen D; Fenaux P; Hokland P; Holm MS; Cazzola M; Malcovati L; Tauro S; Bowen D; Boultwood J; Pellagatti A; Pimanda JE; Unnikrishnan A; Vyas P; Göhring G; Schlegelberger B; Tobiasson M; Kvalheim G; Constantinescu SN; Nerlov C; Nilsson L; Campbell PJ; Sandberg R; Papaemmanuil E; Hellström-Lindberg E; Linnarsson S; Jacobsen SEW
Article: CELL STEM CELL. 2013;13(5):535-548

Lymphomyeloid contribution of an immune-restricted progenitor emerging prior to definitive hematopoietic stem cells.

Böiers C; Carrelha J; Lutteropp M; Luc S; Green JCA; Azzoni E; Woll PS; Mead AJ; Hultquist A; Swiers G; Perdiguero EG; Macaulay IC; Melchiori L; Luis TC; Kharazi S; Bouriez-Jones T; Deng Q; Pontén A; Atkinson D; Jensen CT; Sitnicka E; Geissmann F; Godin I; Sandberg R; de Bruijn MFTR; Jacobsen SEW
Article: NATURE. 2013;502(7470):232-236

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.

Sanjuan-Pla A; Macaulay IC; Jensen CT; Woll PS; Luis TC; Mead A; Moore S; Carella C; Matsuoka S; Bouriez Jones T; Chowdhury O; Stenson L; Lutteropp M; Green JCA; Facchini R; Boukarabila H; Grover A; Gambardella A; Thongjuea S; Carrelha J; Tarrant P; Atkinson D; Clark S-A; Nerlov C; Jacobsen SEW
Article: GENES AND IMMUNITY. 2013;14(7):427-433

Identification of a KIR antisense lncRNA expressed by progenitor cells.

Wright PW; Huehn A; Cichocki F; Li H; Sharma N; Dang H; Lenvik TR; Woll P; Kaufman D; Miller JS; Anderson SK
Article: CELL REPORTS. 2013;3(6):1766-1776

FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.

Mead AJ; Kharazi S; Atkinson D; Macaulay I; Pecquet C; Loughran S; Lutteropp M; Woll P; Chowdhury O; Luc S; Buza-Vidas N; Ferry H; Clark S-A; Goardon N; Vyas P; Constantinescu SN; Sitnicka E; Nerlov C; Jacobsen SEW
Article: BLOOD. 2013;121(20):4156-4165

Impact of isolated germline JAK2V617I mutation on human hematopoiesis.

Mead AJ; Chowdhury O; Pecquet C; Dusa A; Woll P; Atkinson D; Burns A; Score J; Rugless M; Clifford R; Moule S; Bienz N; Vyas P; Cross N; Gale RE; Henderson S; Constantinescu SN; Schuh A; Jacobsen SEW
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2013;160(6):842-850

Silencing of ASXL1 impairs the granulomonocytic lineage potential of human CD34⁺ progenitor cells.

Davies C; Yip BH; Fernandez-Mercado M; Woll PS; Agirre X; Prosper F; Jacobsen SE; Wainscoat JS; Pellagatti A; Boultwood J
Article: BLOOD. 2012;120(12):2412-2416

Dicer is selectively important for the earliest stages of erythroid development.

Buza-Vidas N; Cismasiu VB; Moore S; Mead AJ; Woll PS; Lutteropp M; Melchiori L; Luc S; Bouriez-Jones T; Atkinson D; O'Carroll D; Jacobsen SEW; Nerlov C
Article: NATURE IMMUNOLOGY. 2012;13(4):412-419

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.

Luc S; Luis TC; Boukarabila H; Macaulay IC; Buza-Vidas N; Bouriez-Jones T; Lutteropp M; Woll PS; Loughran SJ; Mead AJ; Hultquist A; Brown J; Mizukami T; Matsuoka S; Ferry H; Anderson K; Duarte S; Atkinson D; Soneji S; Domanski A; Farley A; Sanjuan-Pla A; Carella C; Patient R; de Bruijn M; Enver T; Nerlov C; Blackburn C; Godin I; Jacobsen SEW
Article: BLOOD. 2011;118(6):1544-1548

FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.

Buza-Vidas N; Woll P; Hultquist A; Duarte S; Lutteropp M; Bouriez-Jones T; Ferry H; Luc S; Jacobsen SEW
Article: BLOOD. 2011;118(5):1291-1293

GATA3 is redundant for maintenance and self-renewal of hematopoietic stem cells.

Buza-Vidas N; Duarte S; Luc S; Bouriez-Jones T; Woll PS; Jacobsen SEW
Article: CANCER CELL. 2011;19(1):138-152

Coexistence of LMPP-like and GMP-like leukemia stem cells in acute myeloid leukemia.

Goardon N; Marchi E; Atzberger A; Quek L; Schuh A; Soneji S; Woll P; Mead A; Alford KA; Rout R; Chaudhury S; Gilkes A; Knapper S; Beldjord K; Begum S; Rose S; Geddes N; Griffiths M; Standen G; Sternberg A; Cavenagh J; Hunter H; Bowen D; Killick S; Robinson L; Price A; Macintyre E; Virgo P; Burnett A; Craddock C; Enver T; Jacobsen SEW; Porcher C; Vyas P
Article: NEW ENGLAND JOURNAL OF MEDICINE. 2010;363(11):1025-1037

Persistent malignant stem cells in del(5q) myelodysplasia in remission.

Tehranchi R; Woll PS; Anderson K; Buza-Vidas N; Mizukami T; Mead AJ; Astrand-Grundström I; Strömbeck B; Horvat A; Ferry H; Dhanda RS; Hast R; Rydén T; Vyas P; Göhring G; Schlegelberger B; Johansson B; Hellström-Lindberg E; List A; Nilsson L; Jacobsen SEW
Article: BLOOD. 2009;113(24):6094-6101

Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity.

Woll PS; Grzywacz B; Tian X; Marcus RK; Knorr DA; Verneris MR; Kaufman DS
Article: BLOOD. 2008;112(7):2730-2737

Differences in lymphocyte developmental potential between human embryonic stem cell and umbilical cord blood-derived hematopoietic progenitor cells.

Martin CH; Woll PS; Ni Z; Zúñiga-Pflücker JC; Kaufman DS
Article: BLOOD. 2008;111(1):122-131

Wnt signaling promotes hematoendothelial cell development from human embryonic stem cells.

Woll PS; Morris JK; Painschab MS; Marcus RK; Kohn AD; Biechele TL; Moon RT; Kaufman DS
Article: STEM CELLS. 2007;25(11):2919-2927

Efficient and stable transgene expression in human embryonic stem cells using transposon-mediated gene transfer.

Wilber A; Linehan JL; Tian X; Woll PS; Morris JK; Belur LR; McIvor RS; Kaufman DS
Article: STEM CELLS. 2006;24(5):1370-1380

Hematopoietic engraftment of human embryonic stem cell-derived cells is regulated by recipient innate immunity.

Tian X; Woll PS; Morris JK; Linehan JL; Kaufman DS
Article: JOURNAL OF IMMUNOLOGY. 2005;175(8):5095-5103

Human embryonic stem cell-derived NK cells acquire functional receptors and cytolytic activity.

Woll PS; Martin CH; Miller JS; Kaufman DS
Article: CLINICAL CHEMISTRY. 2005;51(5):907-909

Effect of two common polymorphisms in the ATP binding cassette transporter A1 gene on HDL-cholesterol concentration.

Woll PS; Hanson NQ; Arends VL; Tsai MY
Article: TRANSLATIONAL RESEARCH. 2004;143(6):340-343

Plasma homocysteine levels in living kidney donors before and after uninephrectomy.

Tsai MY; Aras O; Sozen H; Hanson NQ; Woll PS; Arends VL; Hunninghake DB; Matas AJ
Show more

All other publications

Letter: CELL RESEARCH. 2023;33(11):883-886

Platelet and myeloid lineage biases of transplanted single perinatal mouse hematopoietic stem cells.

Belander Strålin K; Carrelha J; Winroth A; Ziegenhain C; Hagemann-Jensen M; Kettyle LM; Hillen A; Högstrand K; Markljung E; Grasso F; Seki M; Mazzi S; Meng Y; Wu B; Chari E; Lehander M; Sandberg R; Woll PS; Jacobsen SEW
Letter: BLOOD ADVANCES. 2022;6(16):4705-4709

The extent of residual WT HSPCs is associated with the degree of anemia in patients with SF3B1-mutated MDS-RS.

Hofman IJF; Mortera-Blanco T; Moura PL; Vestlund J; Larsson SV; Elvarsdottir EM; Walldin G; Tobiasson M; Sander B; Dimitriou M; Jacobsen S-EW; Woll PS; Jädersten M; Hellström-Lindberg E
Review: JOURNAL OF INTERNAL MEDICINE. 2022;292(2):262-277

Targeting stem cells in myelodysplastic syndromes and acute myeloid leukemia.

Woll PS; Yoshizato T; Hellström-Lindberg E; Fioretos T; Ebert BL; Jacobsen SEW
Review: BRITISH JOURNAL OF HAEMATOLOGY. 2019;187(2):144-156

The concept of leukaemic stem cells in acute myeloid leukaemia 25 years on: hitting a moving target.

Hokland P; Woll PS; Hansen MC; Bill M
Letter: LEUKEMIA. 2013;27(5):1204-1207

Quiescent leukaemic cells account for minimal residual disease in childhood lymphoblastic leukaemia.

Lutz C; Woll PS; Hall G; Castor A; Dreau H; Cazzaniga G; Zuna J; Jensen C; Clark SA; Biondi A; Mitchell C; Ferry H; Schuh A; Buckle V; Jacobsen S-EW; Enver T
Letter: CLINICAL CHEMISTRY. 2003;49(3):521-522

Absence of ABCA1 mutations in individuals with low serum HDL-cholesterol.

Woll PS; Hanson NQ; Tsai MY

Research

Articles

All other publications

News from KI

Events from KI