Qiaolin Deng has obtained her professional training in the fields of developmental neurobiology, stem cell biology and single-cell genomics to understand the molecular mechanisms in cell fate specification and transcriptional regulation during embryonic development. Her lab is established in 2015 funded by Young Investigator grants from several funding agencies including Swedish Society for Medical Research, Swedish Medical Research Council and Karolinska Institutet Faculty Fund.
Our research interests focus on the molecular patterning of the epiblast towards the neural plate companied by pluripotency transition and X-chromosome activity regulation. Another major topic is the germ cell reprogramming during migration and the link to the onset of disease or disorder in future generations. To achieve our goals, we aim to combine newly developed concepts with techniques including single-cell transcriptomics and epigenomics, mouse genetics, and advanced computational analyses.
The principles of the normal embryonic development and growth lay the foundation to decipher disease mechanisms. Our research holds a broad biological significance to understand congenital disorders, infertility, and long-term offspring health.
Publications @ Google Scholar
Scientific organizer of EMBO Practical Course: Single-Cell Omics, 2015, 2016, 2017, 2019
Academic honours, awards and prizes
Swedish Medical Research Council (VR) for postdoc employment in Sweden 2011 Swedish Medical Research Council (VR) for Young Investigator Award 2015 Swedish Society for Medical Research (SSMF) for Young Investigator Award 2015 Karolinska Institutet Faculty Funded Assistant Professorship 4+2 year Doctoral funding for recruiting doctoral student, Karolinska Institutet 2015 Jeanssons Stiftelser 2016 Karolinska Institutet Research Foundation Young Investigator grants, 2017 Åke Wiberg Foundation 2016, 2018 Nicholson Exchange Program, Karolinska Institutet-Rockefeller University, 2018 Swedish Medical Research Council (VR) for the project grant 2019