Qing Wang

Publications
CV
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Articles

Article: BLOOD ADVANCES. 2023;7(9):1929-1943

Pirtobrutinib targets BTK C481S in ibrutinib-resistant CLL but second-site BTK mutations lead to resistance.

Naeem A; Utro F; Wang Q; Cha J; Vihinen M; Martindale S; Zhou Y; Ren Y; Tyekucheva S; Kim AS; Fernandes SM; Saksena G; Rhrissorrakrai K; Levovitz C; Danysh BP; Slowik K; Jacobs RA; Davids MS; Lederer JA; Zain R; Smith CIE; Leshchiner I; Parida L; Getz G; Brown JR
Article: LEUKEMIA. 2021;35(5):1317-1329

BTK gatekeeper residue variation combined with cysteine 481 substitution causes super-resistance to irreversible inhibitors acalabrutinib, ibrutinib and zanubrutinib.

Estupiñán HY; Wang Q; Berglöf A; Schaafsma GCP; Shi Y; Zhou L; Mohammad DK; Yu L; Vihinen M; Zain R; Smith CIE
Article: BRITISH JOURNAL OF HAEMATOLOGY. 2018;183(2):212-224

Ibrutinib induces rapid down-regulation of inflammatory markers and altered transcription of chronic lymphocytic leukaemia-related genes in blood and lymph nodes.

Palma M; Krstic A; Peña Perez L; Berglöf A; Meinke S; Wang Q; Blomberg KEM; Kamali-Moghaddam M; Shen Q; Jaremko G; Lundin J; De Paepe A; Höglund P; Kimby E; Österborg A; Månsson R; Smith CIE
Article: BMC PEDIATRICS. 2018;18(1):285

Eleven percent intact PGM3 in a severely immunodeficient patient with a novel splice-site mutation, a case report.

Lundin KE; Wang Q; Hamasy A; Marits P; Uzunel M; Wirta V; Wikström A-C; Fasth A; Ekwall O; Smith CIE
Article: PLOS ONE. 2017;12(4):e0174909

ANKRD54 preferentially selects Bruton's Tyrosine Kinase (BTK) from a Human Src-Homology 3 (SH3) domain library.

Gustafsson MO; Mohammad DK; Ylösmäki E; Choi H; Shrestha S; Wang Q; Nore BF; Saksela K; Smith CIE
Article: LEUKEMIA. 2017;31(1):177-185

Substitution scanning identifies a novel, catalytically active ibrutinib-resistant BTK cysteine 481 to threonine (C481T) variant.

Hamasy A; Wang Q; Blomberg KEM; Mohammad DK; Yu L; Vihinen M; Berglöf A; Smith CIE
Article: PLOS ONE. 2013;8(7):e69784

Histone demethylase retinoblastoma binding protein 2 is overexpressed in hepatocellular carcinoma and negatively regulated by hsa-miR-212.

Liang X; Zeng J; Wang L; Fang M; Wang Q; Zhao M; Xu X; Liu Z; Li W; Liu S; Yu H; Jia J; Chen C

All other publications

KI thesis / dissertation: 2020

Bruton tyrosine kinase in immunodeficiency and in B-cell malignancy

Wang, Qing
Review: CURRENT ALLERGY AND ASTHMA REPORTS. 2015;15(3):510

Splice-correction strategies for treatment of X-linked agammaglobulinemia.

Bestas B; Turunen JJ; Blomberg KEM; Wang Q; Månsson R; El Andaloussi S; Berglöf A; Smith CIE

Employments

Affiliated to Research, Department of Laboratory Medicine, Karolinska Institutet, 2023-2026

Degrees and Education

Degree Of Doctor Of Philosophy, Department of Laboratory Medicine, Karolinska Institutet, 2020

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