About me

My Research

My background is in Biomedicine and currently my main research interests combine biochemistry and redox molecular signaling with anticancer therapy development and evaluation. My expertise includes mechanistic studies involving antioxidant systems and evaluation of novel anticancer drug combinations.

 

Students Representation

I represent MBB doctoral students with the Doctoral Students' Association (DSA, phdsa.se). Please contact me if you are an MBB doctoral student who needs support, has ideas about improving education and workplace environment, or has questions or issues to raise with higher organs within KI. I can help you reach the DSA, as well as the department’s doctoral education responsible persons and administration. 

 

 

Publications

Biochemical and structural characterizations of thioredoxin reductase selenoproteins of the parasitic filarial nematodes Brugia malayi and Onchocerca volvulus. Fata F, Gencheva R, Cheng Q, Lullo R, Ardini M, Silvestri I, Gabriele F, Ippoliti R, Bulman CA, Sakanari JA, Williams DL, Arnér ESJ, Angelucci F Redox Biol 2022 Mar;51():102278

Efficient selenocysteine-dependent reduction of toxoflavin by mammalian thioredoxin reductase. Gencheva R, Cheng Q, Arnér ESJ Biochim Biophys Acta Gen Subj 2018 Nov;1862(11):2511-2517

Comprehensive chemical proteomics analyses reveal that the new TRi-1 and TRi-2 compounds are more specific thioredoxin reductase 1 inhibitors than auranofin. Sabatier P, Beusch CM, Gencheva R, Cheng Q, Zubarev R, Arnér ESJ Redox Biol 2021 Nov;48():102184