About me
Associate Professor (Docent) in molecular epidemiology at the Department of Medical Epidemiology and Biostatistics, Karolinska Institutet.
Research description
My main research interest is human biological aging; how to measure it in human cohorts, understanding causal pathways in aging and identify geroprotectors to repurpose for age-related diseases. Markers of human biological aging can be telomere length, epigenetic clocks, functional aging, frailty index, etc. I study such markers in longitudinal data from several twin studies of aging (SATSA, GENDER, HARMONY, OCTO-Twin, TwinGene) within the Swedish Twin Registry and also using UK biobank data. Methods that I use include longitudinal modelling, causal analyses using drug target Mendelian Randomization, and large-scale genome-wide approaches.
For a more detailed description of my current research please visit my project page A geroscientifc approach to study human biological aging.
Group members
- Chenxi Qin, Postdoc
- Bowen Tang, PhD-student
- Shayan Mostafaei, Bioinformatician
- Yume Imahori, Postdoc
- Jonathan Mak, PhD-student (Co-supervisor)
- Thaís Lopes de Oliveira, Postdoc
- Laura Kananen, Postdoc
- Christian Molnár, PhD-student (Co-supervisor)
- Katalin Vincze, PhD-student (Co-supervisor)
- Sara Licaj, PhD-student (Co-supervisor)
- Daniel Wikström Shemer, student
- Karolina Gustavsson, student
Associated group members
- Ida Karlsson, PhD
- Karolina Kauppi, PhD
- Juulia Jylhävä, PhD
Former group members
- Christopher McMurran, PhD, Visiting researcher
- Ge Bai, PhD-student (Co-supervisor)
- Yunzhang Wang, PhD, bioinformatician
- Xia Li, PhD-student
- Xueying Qin, PhD, visiting researcher
- Ninoa Malki, PhD-student (Co-supervisor)
- Yasutake Tomata, PhD, visiting researcher
- Yiqiang Zhan, PhD-student (Supervisor)
- Xu Chen, PhD-student (Co-supervisor)
- Qi Wang, PhD, visiting researcher
- Robert Muller, Postdoc
- Anne Seeboth, PhD-student (Co-supervisor, University of Edinburgh)
- Dylan Williams, Postdoc
Education
- PhD in Computational Biology, Linköping University, 2009
- MSc in Molecular Biology, Stockholm University, 2003
- BSc in Computer Science, Stockholm University, 2003
Postdoc
- Genetic epidemiology, Medical epidemiology and biostatistics (MEB), KI, 2011-2014
- Molecular epidemiology, Department of medical sciences, Uppsala University, 2013-2014
Sabbatical
- Stanford University School of Medicine, 2016
Academic honours, awards and prizes
Swedish Research Council, National Institute on Aging (NIA/NIH), Strategic Research Program in Epidemiology at Karolinska Institutet, Swedish Cancer Society, King Gustaf V and Queen Victoria’s Foundation of Freemasons, KI Foundations