Sebastian is currently a Postdoctoral Fellow in the King Lab at the Institute for Protein Design, University of Washington, Seattle and affiliated to Karolinska Institutet.
I completed my doctoral studies in the research group of Professor Karin Loré studying how B cell responses are modulated by nanoparticle vaccine formulations. In particular, I studied how the breadth and potency of anti-viral antibody and B cell responses is affected by antigen display. My thesis was titled: "Cellular and molecular mechanisms for induction of broad anti-viral B cell responses through vaccination."
A better understanding of how the immune system interacts with vaccines will allow us to rationally select formulations that have the capacity to elicit stronger immunity and can be advanced into clinical testing. Our studies can ultimately provide information on vaccine antigen persistence, distribution, and the immunological steps for the onset of B cell responses to understand the generation of high-quality and durable antibody responses.
2017-2022 PhD in Medical Science, Karolinska Institutet, Stockholm, Sweden.
2014-2016 Master of Science in Medical Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden.
2010-2014 Bachelor of Science in Biotechnology, KTH Royal Institute of Technology, Stockholm, Sweden.
Academic honours, awards and prizes
2023 Sven Gard Prize for Best Thesis in Virology at Karolinska Institutet in 2022