About me
Shane C. Wright is a postdoctoral researcher supported by the Swedish Society for Medical Research at the Department of Physiology and Pharmacology. He has a background in cell and molecular biology and receptor pharmacology from the University of Toronto (HBSc), the Université Paris VI (MSc) and Karolinska Institutet (PhD; supervisor: Prof. Gunnar Schulte). Shane received postdoctoral training at the Institute for Research in Immunology and Cancer, Université de Montréal (supervisor: Prof. Michel Bouvier) and has since returned to Karolinska Institutet as a senior postdoctoral fellow under the supervision of Assoc. Prof. Volker Lauschke.
Research description
Shane's research focuses on better understanding the action of drugs on receptors known as G protein-coupled receptors (GPCRs). Emerging concepts in receptor pharmacology such as functional selectivity and subcellular signaling have so far not been explored in the context of drug discovery. Employing a biosensor-based approach to map signaling events in fine detail holds great promise for our understanding of drug efficacy and side effects. Combining these tools with patient-derived material will provide much needed insight into the individual variability of patients and the potential for offering better treatments in the future.
Education
Postdoctoral fellow (Personalized medicine and drug development) – Karolinska Institutet (2020 – Present)
Postdoctoral fellow (Biochemistry and Molecular Medicine) – Université de Montréal (2019 – 2020)
Doctor of Philosophy (Receptor biology and signaling) – Karolinska Institutet (2013 – 2019)
Master of Science (Cellular and Molecular Biology) – Université Paris VI (2010 – 2012)
Honours Bachelor of Science (Life sciences) – University of Toronto (2005 – 2010)