About me

I'm a bioinformatician and my research interests are application of advanced statistical methods, Bayesian inference, causal inference, longitudinal and time to event and machine learning algorithms in computational biology, health and medicine. I’m, also, interested in the statistical genetics and analyzing OMICs and longitudinal data from national registry and surveys.

Research description

Advanced Clustering, Regression and Classification Algorithms

Statistical Learning for OMICs data 

Bioinformatics and Statistical Genetics

Longitudinal Statistical Models for high-dimensional data

Survival and Risk Modelling

Bayesian and Network Meta-analysis for GWAS

Model-based linkage and association analysis in genetic epidemiology


Arian F, Amini M, Mostafaei S, Rezaei Kalantari K, Haddadi Avval A, Shahbazi Z, Kasani K, Bitarafan Rajabi A, Chatterjee S, Oveisi M, Shiri I. Myocardial Function Prediction After Coronary Artery Bypass Grafting Using MRI Radiomic Features and Machine Learning Algorithms. Journal of Digital Imaging. 2022 Aug 22:1-1.

Shiri I, Mostafaei S, Avval AH, Salimi Y, Sanaat A, Akhavanallaf A, Arabi H, Rahmim A, Zaidi H. High-Dimensional Multinomial Multiclass Severity Scoring of COVID-19 Pneumonia Using CT Radiomics Features and Machine Learning Algorithms. Scientific Reports. 2022 Sep 1. 12 (14817).

Mostafaei S, Borna H, Emamvirdizadeh A, Arabfard M, Ahmadi A, Salimian J, Salesi M, Azimzadeh Jamalkandi S. Causal Path of COPD Progression-Associated Genes in Different Biological Samples. COPD: Journal of Chronic Obstructive Pulmonary Disease. 2022 Dec 31;19(1):290-9.

Khodabakhshi Z, Amini M, Mostafaei S, Haddadi Avval A, Nazari M, Oveisi M, Shiri I, Zaidi H. Overall survival prediction in renal cell carcinoma patients using computed tomography radiomic and clinical information. Journal of digital imaging. 2021 Oct;34(5):1086-98.

Khodabakhshi Z, Mostafaei S, Arabi H, Oveisi M, Shiri I, Zaidi H. Non-small cell lung carcinoma histopathological subtype phenotyping using high-dimensional multinomial multiclass CT radiomics signature. Computers in biology and medicine. 2021 Sep 1;136:104752.

Riahi P, Kazemnejad A, Mostafaei S, Meguro A, Mizuki N, Ashraf-Ganjouei A, Javinani A, Faezi ST, Shahram F, Mahmoudi M. ERAP1 polymorphisms interactions and their association with Behçet’s disease susceptibly: Application of Model-Based Multifactor Dimension Reduction Algorithm (MB-MDR). PloS one. 2020 Feb 5;15(2):e0227997.

Mostafaei S, Abdollahi H, Dehkordi SK, Shiri I, Razzaghdoust A, Moghaddam SH, Saadipoor A, Koosha F, Cheraghi S, Mahdavi SR. CT imaging markers to improve radiation toxicity prediction in prostate cancer radiotherapy by stacking regression algorithm. La radiologia medica. 2020 Jan;125(1):87-97.

Mostafaei S, Kazemnejad A, Jamalkandi SA, Amirhashchi S, Donnelly SC, Armstrong ME, Doroudian M. Identification of novel genes in human airway epithelial cells associated with chronic obstructive pulmonary disease (COPD) using machine-based learning algorithms. Scientific reports. 2018 Oct 25;8(1):1-20.

Edalatifard M, Akhtari M, Salehi M, Naderi Z, Jamshidi A, Mostafaei S, Najafizadeh SR, Farhadi E, Jalili N, Esfahani M, Rahimi B. Intravenous methylprednisolone pulse as a treatment for hospitalised severe COVID-19 patients: results from a randomised controlled clinical trial. European Respiratory Journal. 2020 Dec 1;56(6).

Shiri I, Salimi Y, Pakbin M, Hajianfar G, Avval AH, Sanaat A, Mostafaei S, Akhavanallaf A, Saberi A, Mansouri Z, Askari D. COVID-19 prognostic modeling using CT radiomic features and machine learning algorithms: Analysis of a multi-institutional dataset of 14,339 patients. Computers in Biology and Medicine. 2022 Jun 1;145:105467.

McElroy AN, Invernizzi R, Laskowska JW, O'Neill A, Doroudian M, Moghoofei M, Mostafaei S, Li F, Przybylski AA, O'Dwyer DN, Bowie AG. Candidate Role for Toll-like Receptor 3 L412F Polymorphism and Infection in Acute Exacerbation of Idiopathic Pulmonary Fibrosis. American journal of respiratory and critical care medicine. 2022 Jan 5(ja).

Hadifar S, Mostafaei S, Behrouzi A, Fateh A, Riahi P, Siadat SD, Vaziri F. Strain-specific behavior of Mycobacterium tuberculosis in A549 lung cancer cell line. BMC bioinformatics. 2021 Dec;22(1):1-2.



Ph.D. in Biostatistics-Department of Biostatistics, Faculty of Medical Sciences, Tarbiat Modares University (TMU), Tehran, Iran, 2018.

Academic honours, awards and prizes

2022 Research Grant - Loo and Hans Osterman Foundation for Medical Research (dnr 2022-01247).

2022 Research Grant - Foundation for Geriatric Diseases at Karolinska Institutet (dnr 2022-01299).

2022 KI Research Foundation Grants 2022-2023 (dnr 2022-01658).

2019 Research Grant- National Institute for Medical Research, Iran (SCAD and MCP Penalized Logistics Regression for Identification of Novel Genes in Human Sputum Cells associated with Chronic Obstructive Pulmonary Disease (COPD) in High-Dimensional Data).

2018 Research Grant- National Institute for Medical Research, Iran (Simultaneous Effects of Viral Factors of HPV and EBV on progression of Breast and Thyroid Cancers: Application of Structural equation modeling).

2017 Research Grant- National Institute for Medical Research, Iran (A Machine Learning and Penalized Generalized Linear Modeling for High-Dimensional Data in Genome-Wide Association Study).

2018 Yong Researcher in Bioinformatics Festival TMU-Tehran, Iran.

2016 Member of Iran's National Genius Foundation.