About me

  • Sirus Rabbani is a medical doctor and Ph.D. student in the Upper GI Surgery
    group at the Department of Molecular Medicine and Surgery, Karolinska
    Institutet. In parallel with his medical studies, he pursued a PhD after
    being granted partial funding from the Karolinska CSTP programme in mid-2018.
    His research focuses on investigating the aetiology of oesophageal cancer,
    especially the role of sex hormones.

Research

  • Oesophageal adenocarcinoma (OAC) carries an extremely poor prognosis with an
    overall 5-year survival lower than 20%. OAC is characterised by a strong and
    largely unexplained male predominance. Our research is mainly investigating
    the role of sex hormones on the incidence and prognosis of OAC.
    *Publications*
    *Rabbani S*, Santoni G, Lagergren J, Xie SH. Use of anti-androgenic
    5α-reductase inhibitors and risk of oesophageal and gastric cancer by
    histological type and anatomical sub-site. Br J Cancer. 2022
    Sep
  • 127(5):892-897.
    Xie SH, *Rabbani S*, Ness-Jensen E, Lagergren J. Circulating Levels of
    Inflammatory and Metabolic Biomarkers and Risk of Esophageal Adenocarcinoma
    and Barrett Esophagus: Systematic Review and Meta-analysis. Cancer Epidemiol
    Biomarkers Prev. 2020 Nov
  • 29(11):2109-2118.
    Xie SH, Ness-Jensen E, *Rabbani S*, Langseth H, Gislefoss RE, Mattsson F,
    Lagergren J. Circulating Sex Hormone Levels and Risk of Esophageal
    Adenocarcinoma in a Prospective Study in Men. Am J Gastroenterol. 2020
    Feb
  • 115(2):216-223.
    Xie SH, *Rabbani S*, Petrick JL, Cook MB, Lagergren J. Racial and Ethnic
    Disparities in the Incidence of Esophageal Cancer in the United States,
    1992-2013. Am J Epidemiol. 2017 Dec 15
  • 186(12):1341-1351.

All other publications

Degrees and Education

  • Degree Of Doctor Of Philosophy, Department of Molecular Medicine and Surgery, Karolinska Institutet, 2023
  • Degree Of Master Of Science In Medicine, Karolinska Institutet, 2020

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