Stefania Koutsilieri is a Ph.D. student in the Laboratory of ‘Personalized Medicine and Drug Development’ in the Physiology and Pharmacology Department of Karolinska Institutet, under the supervision of Assoc. Prof. V.M.Lauschke. After graduating with honors from the Pharmacy School of the National and Kapodistrian University of Athens (NKUA), she completed her Master’s degree in Pharmacology. Stefania has been awarded a Ph.D. scholarship from the Onassis Foundation to pursue research in the fields of Pharmacology and Pharmacogenomics. Her research focuses on the profound characterisation of the signaling pathways activated upon the binding of medications on G protein-coupled receptors (GPCRs) in an effort to gain a better understanding of drug efficacy and side effects. The impact of interpatient variability is also investigated by employing 3D culture models of primary human tissues.
Apart from the research projects in which she is involved, Stefania deeply believes that for Pharmacogenomics to be implemented in the clinic, it is of tremendous importance that regulatory aspects should be taken into consideration as carefully as research itself. To this end, Stefania focuses on the delineation of the similarities and most importantly, the discrepancies between the pharmacogenomic information that is documented in the drug labels approved by the two major regulatory bodies (FDA, EMA) and renowned research consortia, like the Clinical Pharmacogenetics Implementation Consortium.