Tamoghna Mandal

About me
Publications
Public outreach and news

About me

Presently performing postdoc studies on immune checkpoint interactors using
MS-CETSA.

Research

I have worked with malignant transformation of stem cells in breast cancer. Also role of PRC2 complex driven cancer stem cell features. Then I worked
with developing and validating leukemic mouse models for AML and AEL. Understanding transcriptomic plasticity and novel nanoparticle mediated drug targeting systems to target cancer stem cell population. I have been working with different aspects of cancer stem cell biology since 2009. I now work with understanding immune response and signalling with the help of MS-CETSA.

Articles

Article: ONCOLOGY REPORTS. 2023;50(3):166

Efficacy of combined targeted therapy with PI3K and CDK4/6 or PARP and WEE1 inhibitors in neuroblastoma cell lines.

Lukoseviciute M; Holzhauser S; Pappa E; Mandal T; Dalianis T; Kostopoulou ON
Article: BLOOD. 2023;142(1):90-105

A noncanonical enzymatic function of PIWIL4 maintains genomic integrity and leukemic growth in AML.

Bamezai S; Pulikkottil AJ; Yadav T; Vegi NM; Mueller J; Mark J; Mandal T; Feder K; Ihme S; Song C; Rosler R; Wiese S; Hoell JI; Kloetgen A; Karsan A; Kumari A; Wojenski L; Sinha AU; Gonzalez-Menendez I; Quintanilla-Martinez L; Donato E; Trumpp A; Kruse E; Hamperl S; Zou L; Rawat VPS; Buske C
Article: LEUKEMIA. 2022;36(2):416-425

TET3 promotes AML growth and epigenetically regulates glucose metabolism and leukemic stem cell associated pathways.

Pulikkottil AJ; Bamezai S; Ammer T; Mohr F; Feder K; Vegi NM; Mandal T; Kohlhofer U; Quintanilla-Martinez L; Sinha A; Buske C; Rawat VPS
Article: BLOOD ADVANCES. 2019;3(22):3729-3739

The ParaHox gene Cdx4 induces acute erythroid leukemia in mice.

Thoene S; Mandal T; Vegi NM; Quintanilla-Martinez L; Rösler R; Wiese S; Metzeler KH; Herold T; Haferlach T; Döhner K; Döhner H; Schwarzmüller L; Klingmüller U; Buske C; Rawat VPS; Feuring-Buske M
Article: SCIENTIFIC REPORTS. 2018;8(1):989

Targeting murine leukemic stem cells by antibody functionalized mesoporous silica nanoparticles.

Mandal T; Beck M; Kirsten N; Lindén M; Buske C
Article: SMALL. 2017;13(41)

Super-Resolution Microscopy Unveils Dynamic Heterogeneities in Nanoparticle Protein Corona.

Feiner-Gracia N; Beck M; Pujals S; Tosi S; Mandal T; Buske C; Linden M; Albertazzi L
Journal article: EXPERIMENTAL HEMATOLOGY. 2017;53:s80

TARGETING LEUKEMIC STEM CELLS BY ANTIBODY FUNCTIONALIZED MESOPOROUS SILICA NANOPARTICLES IN MURINE AML MODEL

Mandal T; Beck M; Kirsten N; Linden M; Buske C
Article: ACS APPLIED MATERIALS & INTERFACES. 2017;9(22):18566-18574

Serum Protein Adsorption Enhances Active Leukemia Stem Cell Targeting of Mesoporous Silica Nanoparticles.

Beck M; Mandal T; Buske C; Lindén M
Article: ONCOTARGET. 2016;7(52):86889-86901

VENTX induces expansion of primitive erythroid cells and contributes to the development of acute myeloid leukemia in mice.

Gentner E; Vegi NM; Mulaw MA; Mandal T; Bamezai S; Claus R; Tasdogan A; Quintanilla-Martinez L; Grunenberg A; Döhner K; Döhner H; Bullinger L; Haferlach T; Buske C; Rawat VPS; Feuring-Buske M
Article: CELL REPORTS. 2016;16(2):498-507

MEIS2 Is an Oncogenic Partner in AML1-ETO-Positive AML.

Vegi NM; Klappacher J; Oswald F; Mulaw MA; Mandoli A; Thiel VN; Bamezai S; Feder K; Martens JHA; Rawat VPS; Mandal T; Quintanilla-Martinez L; Spiekermann K; Hiddemann W; Döhner K; Döhner H; Stunnenberg HG; Feuring-Buske M; Buske C
Article: BMC CANCER. 2014;14:785

Bmi1 regulates self-renewal and epithelial to mesenchymal transition in breast cancer cells through Nanog.

Paranjape AN; Balaji SA; Mandal T; Krushik EV; Nagaraj P; Mukherjee G; Rangarajan A
Journal article: BIOMEDICINE AND PREVENTIVE NUTRITION. 2014;4(2):151-159

Phenolic constituents in the polar extracts of Lawsonia inermis mitigate antimycin A-induced mitochondrial degenerative cascades in Hep3B cells

Guha G; Mandal T; Bhakta D; Kumar RA
Article: ONCOGENE. 2012;31(15):1896-1909

Introduction of SV40ER and hTERT into mammospheres generates breast cancer cells with stem cell properties.

Paranjape AN; Mandal T; Mukherjee G; Kumar MV; Sengupta K; Rangarajan A
Article: FOOD AND CHEMICAL TOXICOLOGY. 2010;48(12):3449-3457

Antimycin A-induced mitochondrial apoptotic cascade is mitigated by phenolic constituents of Phyllanthus amarus aqueous extract in Hep3B cells.

Guha G; Mandal T; Rajkumar V; Ashok Kumar R

All other publications

Conference publication: ONCOLOGY RESEARCH AND TREATMENT. 2017;40:228

Targeting murine leukemic stem cells by antibody functionalized mesoporous silica nanoparticles in acute myeloid leukemia

Mandal T; Beck M; Kristen N; Linden M; Buske C
Conference publication: BLOOD. 2016;128(22):4713

Targeting of Leukemic Stem Cells By Antibody Functionalized Mesoporous Silica Nanoparticles in a Mouse Model of CALM-AF10 Positive Acute Myeloid Leukemia

Mandal T; Beck M; Linden M; Buske C
Conference publication: HAEMATOLOGICA. 2016;101:36

VENTX INDUCES EXPANSION OF PRIMITIVE ERYTHROID CELLS AND CONTRIBUTES TO THE DEVELOPMENT OF ACUTE MYELOID LEUKEMIA IN MICE

Gentner E; Vegi NM; Mulaw MA; Mandal T; Tasdogan A; Quintanilla-Martinez L; Doehner K; Doehner H; Bullinger L; Haferlach T; Buske C; Rawat VP; Feuring-Buske M

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