About me
Ulla Stenius is a Professor of Occupational Toxicology since 2010 at the Institute of Environmental Medicine (IMM). 2014-2022 she was appointed Head/Director of the same department.
Research description
Chemical carcinogenesis, prevention and risk assessment
The overall goal is to improve the basis of risk assessment of chemical carcinogens.
The CRAB- and Lion-projects investigates a novel approach to cancer risk assessment and cancer discovery which could greatly assist risk assessors with the management of large textual data and aid knowledge discovery.
In other projects we analyze sex differences in response to carcinogens and the carcinogenic effects of silica. The goal of the projects is to improve the scientific base for risk assessment.
Projects
- Using text mining to aid cancer risk assessment
- Gender differences in carcinogenesis
- Cancer risk of low dose exposure for silica
Financing
- FORTE
- Afa
- FORMAS
Five selected publications
ATX-LPA-Dependent Nuclear Translocation of Endonuclease G in Respiratory Epithelial Cells: A New Mode Action for DNA Damage Induced by Crystalline Silica Particles. Zheng H, Stenius U, Högberg J. Cancers (Basel). 2023 Jan 30;15(3):865.
TGF beta promotes repair of bulky DNA damage through increased ERCC1/XPF and ERCC1/XPA interaction. Zheng H, Jarvis IWH, Bottai M, Dreij K, Stenius U. Carcinogenesis. 2019 Jun 10;40(4):580-591.
LION LBD: a literature-based discovery system for cancer biology. Pyysalo S, Baker S, Ali I, Haselwimmer S, Shah T, Young A, Guo Y, Högberg J, Stenius U, Narita M, Korhonen A. Bioinformatics. 2019 May 1;35(9):1553-1561
Cancer Hallmarks Analytics Tool (CHAT): a text mining approach to organize and evaluate scientific literature on cancer. Baker S, Ali I, Silins I, Pyysalo S, Guo Y, Högberg J, Stenius U, Korhonen A. Bioinformatics. 2017 Dec 15;33(24):3973-3981
Gender differences in cancer susceptibility: role of oxidative stress. Ali I, Högberg J, Hsieh J, Auerbach S, Korhonen A, Stenius U, et al Carcinogenesis 2016 Oct;37(10):985-992