Vijole Ottosson

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CV
Public outreach and news

Articles

Article: ANNALS OF THE RHEUMATIC DISEASES. 2022;81(8):1151-1161

Auxilin is a novel susceptibility gene for congenital heart block which directly impacts fetal heart function.

Meisgen S; Hedlund M; Ambrosi A; Folkersen L; Ottosson V; Forsberg D; Thorlacius GE; Biavati L; Strandberg L; Mofors J; Ramskold D; Ruhrmann S; Meneghel L; Nyberg W; Espinosa A; Hamilton RM; Franco-Cereceda A; Hamsten A; Olsson T; Greene L; Eriksson P; Gemzell-Danielsson K; Salomonsson S; Kuchroo VK; Herlenius E; Kockum I; Sonesson S-E; Wahren-Herlenius M
Article: ANNALS OF THE RHEUMATIC DISEASES. 2021;80(2):194-202

Natural killer cells and type II interferon in Ro/SSA and La/SSB autoantibody-exposed newborns at risk of congenital heart block.

Ivanchenko M; Thorlacius GE; Hedlund M; Ottosson V; Meneghel L; Björkander S; Ossoinak A; Tingström J; Bremme K; Sverremark-Ekström E; Gemzell-Danielsson K; Sonesson S-E; Chemin K; Wahren-Herlenius M
Article: RMD OPEN. 2020;6(1):e000989

Type I IFN system activation in newborns exposed to Ro/SSA and La/SSB autoantibodies in utero.

Hedlund M; Thorlacius GE; Ivanchenko M; Ottosson V; Kyriakidis N; Lagnefeldt L; Tingström J; Sirsjö A; Bengtsson AA; Aronsson E; Gemzell-Danielsson K; Ronnblom L; Bergman G; Espinosa A; Sonesson S-E; Eloranta M-L; Wahren-Herlenius M
Article: EXPERIMENTAL DERMATOLOGY. 2017;26(8):713-720

TRIM21 is important in the early phase of inflammation in the imiquimod-induced psoriasis-like skin inflammation mouse model.

Vinter H; Langkilde A; Ottosson V; Espinosa A; Wahren-Herlenius M; Raaby L; Johansen C; Iversen L
Article: CLINICAL AND EXPERIMENTAL IMMUNOLOGY. 2016;186(3):284-291

Identification of discrete epitopes of Ro52p200 and association with fetal cardiac conduction system manifestations in a rodent model.

Hoxha A; Ruffatti A; Ambrosi A; Ottosson V; Hedlund M; Ottosson L; Anandapadamanaban M; Sunnerhagen M; Sonesson S-E; Wahren-Herlenius M
Article: SCANDINAVIAN JOURNAL OF RHEUMATOLOGY. 2015;44(2):135-142

Incident cases of primary Sjögren's syndrome during a 5-year period in Stockholm County: a descriptive study of the patients and their characteristics.

Kvarnström M; Ottosson V; Nordmark B; Wahren-Herlenius M
Article: ACTA PAEDIATRICA. 2014;103(3):275-281

Late development of complete atrioventricular block may be immune mediated and congenital in origin.

Bergman G; Skog A; Tingström J; Ottosson V; Hoxha A; Ambrosi A; Swedish Congenital Heart Block Study Group; Salomonsson S; Wahren-Herlenius M
Article: LUPUS. 2013;22(5):477-485

Autoantibodies to the functionally active RING-domain of Ro52/SSA are associated with disease activity in patients with lupus.

Kvarnström M; Dzikaite-Ottosson V; Ottosson L; Gustafsson JT; Gunnarsson I; Svenungsson E; Wahren-Herlenius M
Article: ANNALS OF THE RHEUMATIC DISEASES. 2012;71(3):448-454

Anti-Ro52 monoclonal antibodies specific for amino acid 200-239, but not other Ro52 epitopes, induce congenital heart block in a rat model.

Ambrosi A; Dzikaite V; Park J; Strandberg L; Kuchroo VK; Herlenius E; Wahren-Herlenius M
Article: ANNALS OF THE RHEUMATIC DISEASES. 2012;71(3):334-340

Development of heart block in children of SSA/SSB-autoantibody-positive women is associated with maternal age and displays a season-of-birth pattern.

Ambrosi A; Salomonsson S; Eliasson H; Zeffer E; Skog A; Dzikaite V; Bergman G; Fernlund E; Tingström J; Theander E; Rydberg A; Skogh T; Öhman A; Lundström U; Mellander M; Winqvist O; Fored M; Ekbom A; Alfredsson L; Källberg H; Olsson T; Gadler F; Jonzon A; Kockum I; Sonesson S-E; Wahren-Herlenius M
Article: SCANDINAVIAN JOURNAL OF IMMUNOLOGY. 2011;74(5):511-517

A population-based investigation of the autoantibody profile in mothers of children with atrioventricular block.

Salomonsson S; Dzikaite V; Zeffer E; Eliasson H; Ambrosi A; Bergman G; Fernlund E; Theander E; Ohman A; Rydberg A; Skogh T; Wållberg-Jonsson S; Elfving A; Fored M; Ekbom A; Lundström U; Mellander M; Winqvist O; Sonesson S-E; Gadler F; Jonzon A; Wahren-Herlenius M
Article: JOURNAL OF IMMUNOLOGY. 2010;185(6):3574-3582

Maternal MHC regulates generation of pathogenic antibodies and fetal MHC-encoded genes determine susceptibility in congenital heart block.

Strandberg LS; Ambrosi A; Jagodic M; Dzikaite V; Janson P; Khademi M; Salomonsson S; Ottosson L; Klauninger R; Adén U; Sonesson S-E; Sunnerhagen M; de Graaf KL; Kuchroo VK; Achour A; Winqvist O; Olsson T; Wahren-Herlenius M
Article: LIVER INTERNATIONAL. 2006;26(8):976-985

Expression of iron regulatory genes in a rat model of hepatocellular carcinoma.

Holmström P; Gåfvels M; Eriksson LC; Dzikaite V; Hultcrantz R; Eggertsen G; Stål P
Article: JOURNAL OF HEPATOLOGY. 2006;44(3):544-551

Regulatory effects of tumor necrosis factor-alpha and interleukin-6 on HAMP expression in iron loaded rat hepatocytes.

Dzikaite V; Holmström P; Stål P; Eckes K; Hagen K; Eggertsen G; Gåfvels M; Melefors O; Hultcrantz R
Article: BIOCHIMICA ET BIOPHYSICA ACTA: INTERNATIONAL JOURNAL OF BIOCHEMISTRY AND BIOPHYSICS. 2003;1630(1):19-24

The regulatory effect of heme on erythroid aminolevulinate synthase in natural erythroid cells.

Dzikaite V; Hultcrantz R; Melefors O
Article: JOURNAL OF HEPATOLOGY. 2003;39(3):308-314

Structure and liver cell expression pattern of the HFE gene in the rat.

Holmström P; Dzikaite V; Hultcrantz R; Melefors O; Eckes K; Stål P; Kinnman N; Smedsrød B; Gåfvels M; Eggertsen G
Article: BLOOD. 2000;96(2):740-746

A novel endoproteolytic processing activity in mitochondria of erythroid cells and the role in heme synthesis.

Dzikaite V; Kanopka A; Brock JH; Kazlauskas A; Melefors O

Employments

Laboratory Manager, Department of Medicine, Karolinska Institutet, 2006-

Degrees and Education

Doctor Of Philosophy, Department of Medicine, Solna, Karolinska Institutet, 2004

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