Xiaojun Xu

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Articles

Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2013;721(1-3):5-11

Analgesic effect of sinomenine in rodents after inflammation and nerve injury.

Gao T; Hao J; Wiesenfeld-Hallin Z; Wang D-Q; Xu X-J
Article: ZHONGGUO ZHONGYAO ZAZHI. 2013;38(20):3554-3559

[Analgesic effect of CQM on prosopalgia model rats and its impact on exciting amino acid neurotransmitters].

Wang Y; Wang D-Q; Cui Y; Zhang Y; Sun D-D; Zhao X-L; Liu Y; Zhang M-Y; Jiao Y; Xu X-J; Xu S
Article: JOURNAL OF NEUROSCIENCE METHODS. 2013;212(2):317-321

Quantitative test of responses to thermal stimulation in spinally injured rats using a Peltier thermode: a new approach to study cold allodynia.

Gao T; Hao J-X; Wiesenfeld-Hallin Z; Xu X-J
Article: EUROPEAN JOURNAL OF PAIN. 2012;16(10):1368-1377

Genetic and sex influence on neuropathic pain-like behaviour after spinal cord injury in the rat.

Dominguez CA; Ström M; Gao T; Zhang L; Olsson T; Wiesenfeld-Hallin Z; Xu X-J; Piehl F
Article: EXPERIMENTAL NEUROLOGY. 2012;237(2):260-266

Meteorin reverses hypersensitivity in rat models of neuropathic pain.

Jørgensen JR; Xu X-J; Arnold HM; Munro G; Hao J-X; Pepinsky B; Huang C; Gong BJ; Wiesenfeld-Hallin Z; Wahlberg LU; Johansen TE
Article: NEUROSCIENCE LETTERS. 2012;511(1):4-7

Heparanase overexpression reduces carrageenan-induced mechanical and cold hypersensitivity in mice.

Li L; Wang B; Gao T; Zhang X; Hao J-X; Vlodavsky I; Wiesenfeld-Hallin Z; Xu X-J; Li J-P
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2011;34(10):1529-1541

Dependence on the transcription factor Shox2 for specification of sensory neurons conveying discriminative touch.

Abdo H; Li L; Lallemend F; Bachy I; Xu X-J; Rice FL; Ernfors P
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2011;33(8):1385-1400

Essential role of Ret for defining non-peptidergic nociceptor phenotypes and functions in the adult mouse.

Franck MCM; Stenqvist A; Li L; Hao J; Usoskin D; Xu X; Wiesenfeld-Hallin Z; Ernfors P
Article: NEUROSCIENCE. 2010;170(3):923-928

Peripheral adenosine A2A receptors are involved in carrageenan-induced mechanical hyperalgesia in mice.

Li L; Hao JX; Fredholm BB; Schulte G; Wiesenfeld-Hallin Z; Xu XJ
Article: JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM. 2010;15(1):26-39

Expression of DRG candidate pain molecules after nerve injury--a comparative study among five inbred mouse strains with contrasting pain phenotypes.

Persson A-K; Xu X-J; Wiesenfeld-Hallin Z; Devor M; Fried K
Article: BRAIN RESEARCH. 2009;1285:1-13

Autotomy behavior correlates with the DRG and spinal expression of sodium channels in inbred mouse strains.

Persson A-K; Thun J; Xu X-J; Wiesenfeld-Hallin Z; Ström M; Devor M; Lidman O; Fried K
Article: PAIN. 2009;143(1-2):37-40

Ablation of estrogen receptor alpha or beta eliminates sex differences in mechanical pain threshold in normal and inflamed mice.

Li L; Fan X; Warner M; Xu X-J; Gustafsson J-A; Wiesenfeld-Hallin Z
Article: MOLECULAR PAIN. 2009;5:1744-8069-5-7

Correlational analysis for identifying genes whose regulation contributes to chronic neuropathic pain.

Persson A-K; Gebauer M; Jordan S; Metz-Weidmann C; Schulte AM; Schneider H-C; Ding-Pfennigdorff D; Thun J; Xu X-J; Wiesenfeld-Hallin Z; Darvasi A; Fried K; Devor M
Article: GENDER MEDICINE. 2009;6 Suppl 2:225-234

Sex differences in the development of localized and spread mechanical hypersensitivity in rats after injury to the infraorbital or sciatic nerves to create a model for neuropathic pain.

Dominguez CA; Kouya PF; Wu W-P; Hao J-X; Xu X-J; Wiesenfeld-Hallin Z
Article: NEUROSCIENCE LETTERS. 2008;443(2):95-98

Contrasting genetic effects of major histocompatibility complex on ischemic peripheral nerve and spinal cord injury in female rats.

Dominguez CA; Lidman O; Olsson T; Wiesenfeld-Hallin Z; Piehl F; Xu X-J
Article: LAKARTIDNINGEN. 2008;105(39):2678-2682

[Genetics of neuropathic pain].

Fried K; Persson A-KM; Xu X-J; Wiesenfeld-Hallin Z
Article: NEUROSCIENCE LETTERS. 2008;442(3):284-286

Both MHC and non-MHC genes regulate development of experimental neuropathic pain in rats.

Dominguez CA; Li L; Lidman O; Olsson T; Wiesenfeld-Hallin Z; Piehl F; Xu X-J
Article: PAIN. 2008;138(2):292-300

Functional MRI of the brain detects neuropathic pain in experimental spinal cord injury.

Endo T; Spenger C; Hao J; Tominaga T; Wiesenfeld-Hallin Z; Olson L; Xu X-J
Article: PAIN. 2008;136(3):313-319

Genetic analysis of neuropathic pain-like behavior following peripheral nerve injury suggests a role of the major histocompatibility complex in development of allodynia.

Dominguez CA; Lidman O; Hao J-X; Diez M; Tuncel J; Olsson T; Wiesenfeld-Hallin Z; Piehl F; Xu X-J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2006;553(1-3):135-140

Lacosamide, a new anti-epileptic, alleviates neuropathic pain-like behaviors in rat models of spinal cord or trigeminal nerve injury.

Hao J-X; Stöhr T; Selve N; Wiesenfeld-Hallin Z; Xu X-J
Article: NEUROSCIENCE LETTERS. 2006;402(1-2):164-166

Effect of acute and chronic administration of caffeine on pain-like behaviors in rats with partial sciatic nerve injury.

Wu W-P; Hao J-X; Fredholm BB; Wiesenfeld-Hallin Z; Xu X-J
Article: PAIN. 2005;119(1-3):82-94

Behavioral changes and trigeminal ganglion sodium channel regulation in an orofacial neuropathic pain model.

Eriksson J; Jablonski A; Persson A-K; Hao J-X; Kouya PF; Wiesenfeld-Hallin Z; Xu X-J; Fried K
Article: PAIN. 2005;116(3):347-358

Comparative actions of the opioid analgesics morphine, methadone and codeine in rat models of peripheral and central neuropathic pain.

Erichsen HK; Hao J-X; Xu X-J; Blackburn-Munro G
Article: INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS. 2005;11(1):17-27

A galanin receptor subtype 1 specific agonist

Lundström L; Sollenberg U; Brewer A; Kouya PF; Zheng K; Xu XJ; Sheng X; Robinson JK; Wiesenfeld-Hallin Z; Xu ZQ; Hökfelt T; Bartfai T; Langel Ü
Article: PAIN. 2005;113(3):395-404

Increased nociceptive response in mice lacking the adenosine A1 receptor.

Wu W-P; Hao J-X; Halldner L; Lövdahl C; DeLander GE; Wiesenfeld-Hallin Z; Fredholm BB; Xu X-J
Article: BRAIN RESEARCH. 2004;1025(1-2):152-158

Galanin over-expression decreases the development of neuropathic pain-like behaviors in mice after partial sciatic nerve injury.

Hygge-Blakeman K; Brumovsky P; Hao J-X; Xu X-J; Hökfelt T; Crawley JN; Wiesenfeld-Hallin Z
Article: JOURNAL OF NEUROPHYSIOLOGY. 2004;92(3):1391-1399

Response characteristics of spinal cord dorsal horn neurons in chronic allodynic rats after spinal cord injury.

Hao J-X; Kupers RC; Xu X-J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2004;497(1):29-33

High-efficacy 5-HT1A receptor activation causes a curative-like action on allodynia in rats with spinal cord injury.

Colpaert FC; Wu W-P; Hao J-X; Royer I; Sautel F; Wiesenfeld-Hallin Z; Xu X-J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2004;492(1):27-34

Comparison of the antinociceptive effect of morphine, methadone, buprenorphine and codeine in two substrains of Sprague-Dawley rats.

Bulka A; Kouya PF; Böttiger Y; Svensson J-O; Xu X-J; Wiesenfeld-Hallin Z
Article: NEUROSCIENCE LETTERS. 2004;359(1-2):127-129

Buprenorphine reduces central sensitization after repetitive C-fiber stimulation in rats.

Kouya PF; Xu X-J
Article: JOURNAL OF NEUROSCIENCE METHODS. 2004;133(1-2):65-69

Chronic lumbar catheterization of the spinal subarachnoid space in mice.

Wu W-P; Xu X-J; Hao J-X
Article: BRITISH JOURNAL OF PHARMACOLOGY. 2004;141(1):65-74

A nitric oxide (NO)-releasing derivative of gabapentin, NCX 8001, alleviates neuropathic pain-like behavior after spinal cord and peripheral nerve injury.

Wu W-P; Hao J-X; Ongini E; Impagnatiello F; Presotto C; Wiesenfeld-Hallin Z; Xu X-J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2003;482(1-3):133-137

Systemic galnon, a low-molecular weight galanin receptor agonist, reduces heat hyperalgesia in rats with nerve injury.

Wu W-P; Hao J-X; Lundström L; Wiesenfeld-Hallin Z; Langel U; Bartfai T; Xu X-J
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2003;478(2-3):131-137

The very-high-efficacy 5-HT1A receptor agonist, F 13640, preempts the development of allodynia-like behaviors in rats with spinal cord injury.

Wu W-P; Hao J-X; Xu X-J; Wiesenfeld-Hallin Z; Koek W; Colpaert FC
Article: JOURNAL OF REHABILITATION MEDICINE. 2003;(41 Suppl):81-84

Animal models of spinal cord injury pain and their implications for pharmacological treatments.

Hao J-X; Xu X-J
Article: NEUROSCIENCE LETTERS. 2003;345(3):153-156

Flexor reflex excitability in mice lacking galanin receptor galanin-R1.

Grass S; Jacoby AS; Iismaa TP; Crawley JN; Xu X-J; Wiesenfeld-Hallin Z
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 2003;17(9):1829-1832

Reduced spinal cord sensitization to C-fibre stimulation in mice over-expressing galanin.

Grass S; Crawley JN; Xu X-J; Wiesenfeld-Hallin Z
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2003;458(3):275-282

A comparison of the antinociceptive effects of voltage-activated Na+ channel blockers in two rat models of neuropathic pain.

Erichsen HK; Hao J-X; Xu X-J; Blackburn-Munro G
Article: NEUROSCIENCE. 2003;117(1):221-227

Hyperalgesia and increased neuropathic pain-like response in mice lacking galanin receptor 1 receptors.

Blakeman KH; Hao J-X; Xu X-J; Jacoby AS; Shine J; Crawley JN; Iismaa T; Wiesenfeld-Hallin Z
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 2002;91(6):398-403

The role of spinal cholecystokinin in chronic pain states.

Wiesenfeld-Hallin Z; Xu X-J; Hökfelt T
Article: NEUROPHARMACOLOGY. 2002;43(6):945-958

Large-amplitude 5-HT1A receptor activation: a new mechanism of profound, central analgesia.

Colpaert FC; Tarayre JP; Koek W; Pauwels PJ; Bardin L; Xu X-J; Wiesenfeld-Hallin Z; Cosi C; Carilla-Durand E; Assié MB; Vacher B
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 2002;450(1):49-53

Buprenorphine alleviates neuropathic pain-like behaviors in rats after spinal cord and peripheral nerve injury.

Kouya PF; Hao J-X; Xu X-J
Article: BRAIN RESEARCH. 2002;942(1-2):95-100

Differential antinociception by morphine and methadone in two sub-strains of Sprague-Dawley rats and its potentiation by dextromethorphan.

Bulka A; Wiesenfeld-Hallin Z; Xu XJ
Article: NEUROSCIENCE LETTERS. 2002;324(3):197-200

Comparison of the effect of intrathecal endomorphin-1 and endomorphin-2 on spinal cord excitability in rats.

Grass S; Xu IS; Wiesenfeld-Hallin Z; Xu XJ
Article: NEUROPEPTIDES. 2002;36(2-3):145-156

Galanin overexpressing transgenic mice.

Crawley JN; Mufson EJ; Hohmann JG; Teklemichael D; Steiner RA; Holmberg K; Xu Z-QD; Blakeman KH; Xu X-J; Wiesenfeld-Hallin Z; Bartfai T; Hökfelt T
Article: LIFE SCIENCES. 2002;70(10):1151-1157

Intrathecal [Nphe1]nociceptin( 1-13)NH2 selectively reduces the spinal inhibitory effect of nociceptin.

Xu IS; Grass S; Calo G; Guerrini R; Wiesenfeld-Hallin Z; Xu X-J
Article: NEUROSCIENCE. 2002;114(3):523-527

Decreased inflammatory pain due to reduced carrageenan-induced inflammation in mice lacking adenosine A3 receptors.

Wu W-P; Hao J-X; Halldner-Henriksson L; Xu X-J; Jacobson MA; Wiesenfeld-Hallin Z; Fredholm BB
Article: PAIN. 2002;95(1-2):103-109

Reduced tolerance to the anti-hyperalgesic effect of methadone in comparison to morphine in a rat model of mononeuropathy.

Bulka A; Plesan A; Xu XJ; Wiesenfeld-Hallin Z
Article: PEPTIDES. 2001;22(8):1305-1308

Increased level of cholecystokinin in cerebrospinal fluid is associated with chronic pain-like behavior in spinally injured rats.

Xu XJ; Alster P; Wu WP; Hao JX; Wiesenfeld-Hallin Z
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2001;98(16):9407-9412

Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptor.

Johansson B; Halldner L; Dunwiddie TV; Masino SA; Poelchen W; Giménez-Llort L; Escorihuela RM; Fernández-Teruel A; Wiesenfeld-Hallin Z; Xu XJ; Hårdemark A; Betsholtz C; Herlenius E; Fredholm BB
Article: NEUROREPORT. 2001;12(2):423-425

Mice over-expressing galanin have elevated heat nociceptive threshold.

Blakeman KH; Holmberg K; Hao JX; Xu XJ; Kahl U; Lendahl U; Bartfai T; Wiesenfeld-Hallin Z; Hökfelt T
Article: NEUROREPORT. 2001;12(2):317-320

Intrathecal administration of PNA targeting galanin receptor reduces galanin-mediated inhibitory effect in the rat spinal cord.

Rezaei K; Xu IS; Wu WP; Shi TJ; Soomets U; Land T; Xu XJ; Wiesenfeld-Hallin Z; Hökfelt T; Bartfai T; Langel U
Article: NATURE. 2001;409(6819):513-517

Reduced antinociception and plasma extravasation in mice lacking a neuropeptide Y receptor.

Naveilhan P; Hassani H; Lucas G; Blakeman KH; Hao JX; Xu XJ; Wiesenfeld-Hallin Z; Thorén P; Ernfors P
Article: PAIN. 2001;89(2-3):135-145

Possible impact of genetic differences on the development of neuropathic pain-like behaviors after unilateral sciatic nerve ischemic injury in rats.

Xu XJ; Plesan A; Yu W; Hao JX; Wiesenfeld-Hallin Z
Article: EUROPEAN JOURNAL OF PAIN. 2001;5(1):1-10

Effects of intrathecal morphine, baclofen, clonidine and R-PIA on the acute allodynia-like behaviours after spinal cord ischaemia in rats.

von Heijne M; Hao JX; Sollevi A; Xu XJ
Article: JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM. 2000;5(4):209-217

Photochemically-induced ischemic injury of the rat sciatic nerve: a light- and electron microscopic study.

Yu W; Kauppila T; Hultenby K; Persson JK; Xu XJ; Wiesenfeld-Hallin Z
Article: PEPTIDES. 2000;21(7):1031-1036

Nociceptin/orphanin FQ in spinal nociceptive mechanisms under normal and pathological conditions.

Xu X; Grass S; Hao J; Xu IS; Wiesenfeld-Hallin Z
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 2000;44(6):665-671

Marked enhancement of anti-allodynic effect by combined intrathecal administration of the adenosine A1-receptor agonist R-phenylisopropyladenosine and morphine in a rat model of central pain.

von Heijne M; Hao JX; Sollevi A; Xu XJ; Wiesenfeld-Hallin Z
Article: NEUROSCIENCE LETTERS. 2000;286(3):208-212

Intracerebroventricular infusion of nerve growth factor induces pain-like response in rats.

Hao J; Ebendal T; Xu X; Wiesenfeld-Hallin Z; Eriksdotter Jönhagen M
Article: EXPERIMENTAL NEUROLOGY. 2000;163(1):231-238

Development of a mouse model of neuropathic pain following photochemically induced ischemia in the sciatic nerve.

Hao JX; Blakeman KH; Yu W; Hultenby K; Xu XJ; Wiesenfeld-Hallin Z
Article: NEUROSCIENCE LETTERS. 2000;280(3):211-214

Repeated administration of systemic gabapentin alleviates allodynia-like behaviors in spinally injured rats.

Hao JX; Xu XJ; Urban L; Wiesenfeld-Hallin Z
Article: EUROPEAN JOURNAL OF PAIN. 2000;4(4):409-412

Lack of stereoselectivity for the antiallodynic effect of mexiletine in spinally injured rats.

Wu WP; Nordmark J; Wiesenfeld-Hallin Z; Xu XJ
Article: NEUROSCIENCE. 2000;98(2):339-344

The effect of intrathecal endomorphin-2 on the flexor reflex in normal, inflamed and axotomized rats: reduced effect in rats with autotomy.

Grass S; Wiesenfeld-Hallin Z; Xu XJ
Article: PAIN. 2000;84(1):21-28

Increased spinal cholecystokinin activity after systemic resiniferatoxin: electrophysiological and in situ hybridization studies.

Broberger C; Farkas-Szallasi T; Szallasi A; Lundberg JM; Hökfelt T; Wiesenfeld-Hallin Z; Xu X-J
Article: NEUROREPORT. 1999;10(17):3681-3684

Effects of intrathecal nocistatin on the flexor reflex and its interaction with orphanin FQ nociceptin.

Xu IS; Hashemi M; Caló G; Regoli D; Wiesenfeld-Hallin Z; Xu XJ
Article: ACTA ANAESTHESIOLOGICA SCANDINAVICA. 1999;43(10):1027-1034

Effects of intrathecal morphine, clonidine and baclofen on allodynia after partial sciatic nerve injury in the rat.

Hao JX; Xu IS; Xu XJ; Wiesenfeld-Hallin Z
Article: NEUROREPORT. 1999;10(15):3247-3251

Intrathecal adenosine does not relieve allodynia-like behavior in spinally injured rats.

von Heijne M; Hao JX; Sollevi A; Xu XJ
Article: BRAIN RESEARCH. 1999;833(2):251-257

The effect of intrathecal selective agonists of Y1 and Y2 neuropeptide Y receptors on the flexor reflex in normal and axotomized rats.

Xu IS; Hao JX; Xu XJ; Hökfelt T; Wiesenfeld-Hallin Z
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1999;370(1):17-22

Effects of intrathecal orphanin FQ on a flexor reflex in the rat after inflammation or peripheral nerve section.

Xu IS; Grass S; Wiesenfeld-Hallin Z; Xu XJ
Article: NEUROSCIENCE LETTERS. 1999;263(1):53-56

Genetic differences in the antinociceptive effect of morphine and its potentiation by dextromethorphan in rats.

Plesan A; Hoffmann O; Xu XJ; Wiesenfeld-Hallin Z
Article: EUROPEAN JOURNAL OF NEUROSCIENCE. 1999;11(2):427-432

Intrathecal galanin alleviates allodynia-like behaviour in rats after partial peripheral nerve injury.

Hao JX; Shi TJ; Xu IS; Kaupilla T; Xu XJ; Hökfelt T; Bartfai T; Wiesenfeld-Hallin Z
Article: NEUROREPORT. 1999;10(1):87-91

Spinal cord ischemia reduces mu-opioid receptors in rats: correlation with morphine insensitivity.

Yu W; Hao JX; Xu XJ; Hökfelt T; Elde R; Wiesenfeld-Hallin Z
Article: ANESTHESIA AND ANALGESIA. 1998;87(6):1367-1371

Reduced anti-allodynic effect of the adenosine A1-receptor agonist R-phenylisopropyladenosine on repeated intrathecal administration and lack of cross-tolerance with morphine in a rat model of central pain.

von Heijne M; Hao JX; Yu W; Sollevi A; Xu XJ; Wiesenfeld-Hallin Z
Article: NEUROPEPTIDES. 1998;32(5):447-452

The effect of intrathecal neuropeptide Y on the flexor reflex in rats after carrageenan-induced inflammation.

Xu IS; Luo L; Ji RR; Hökfelt T; Xu XJ; Wiesenfeld-Hallin Z
Article: NATURE BIOTECHNOLOGY. 1998;16(9):857-861

Cell penetrating PNA constructs regulate galanin receptor levels and modify pain transmission in vivo.

Pooga M; Soomets U; Hällbrink M; Valkna A; Saar K; Rezaei K; Kahl U; Hao JX; Xu XJ; Wiesenfeld-Hallin Z; Hökfelt T; Bartfai T; Langel U
Article: NEUROSCIENCE. 1998;85(3):827-835

On the role of galanin in mediating spinal flexor reflex excitability in inflammation.

Xu IS; Grass S; Xu XJ; Wiesenfeld-Hallin Z
Article: NEUROSCIENCE LETTERS. 1998;249(2-3):127-130

[Phe1psi(CH2-NH)Gly2]-nociceptin-(1-13)NH2, a proposed antagonist of the nociceptin receptor, is a potent and stable agonist in the rat spinal cord.

Xu IS; Wiesenfeld-Hallin Z; Xu XJ
Article: PAIN. 1998;76(3):385-393

Anti-hyperalgesic and anti-allodynic effects of intrathecal nociceptin/orphanin FQ in rats after spinal cord injury, peripheral nerve injury and inflammation.

Hao J-X; Xu IS; Wiesenfeld-Hallin Z; Xu X-J
Article: PAIN. 1998;76(1-2):45-59

Photochemically-induced ischemia of the rat sciatic nerve produces a dose-dependent and highly reproducible mechanical, heat and cold allodynia, and signs of spontaneous pain.

Kupers R; Yu W; Persson JK; Xu XJ; Wiesenfeld-Hallin Z
Article: NEUROREPORT. 1998;9(6):1071-1074

Dextromethorphan potentiates the effect of morphine in rats with peripheral neuropathy.

Kauppila T; Xu XJ; Yu W; Wiesenfeld-Hallin Z
Article: PAIN. 1998;75(2-3):209-217

Treatment of chronic allodynia in spinally injured rats: effects of intrathecal selective opioid receptor agonists.

Hao JX; Yu W; Wiesenfeld-Hallin Z; Xu XJ
Article: ANESTHESIA AND ANALGESIA. 1998;86(4):825-829

Comparison of ketamine and dextromethorphan in potentiating the antinociceptive effect of morphine in rats.

Plesan A; Hedman U; Xu XJ; Wiesenfeld-Hallin Z
Article: NEUROSCIENCE LETTERS. 1998;243(1-3):89-92

Intrathecal administration of the adenosine A1 receptor agonist R-phenylisopropyl adenosine reduces presumed pain behaviour in a rat model of central pain.

Sjölund KF; von Heijne M; Hao JX; Xu XJ; Sollevi A; Wiesenfeld-Hallin Z
Article: NEUROPEPTIDES. 1998;32(1):73-78

On the role of cholecystokinin in the mediation of spinal reflex excitability in intact and axotomized rats.

Lucas GA; Xu XJ; Wiesenfeld-Hallin Z
Article: PAIN. 1998;74(2-3):115-122

Long-term alleviation of allodynia-like behaviors by intrathecal implantation of bovine chromaffin cells in rats with spinal cord injury.

Yu W; Hao JX; Xu XJ; Saydoff J; Haegerstrand A; Hökfelt T; Wiesenfeld-Hallin Z
Article: EXPERIMENTAL BRAIN RESEARCH. 1998;118(2):259-268

Evidence that spinal endogenous opioidergic systems control the expression of chronic pain-related behaviors in spinally injured rats.

Hao JX; Yu W; Xu XJ
Article: EUROPEAN JOURNAL OF PAIN. 1998;2(2):143-151

Immunoisolating encapsulation of intrathecally implanted bovine chromaffin cells prolongs their survival and produces anti-allodynic effect in spinally injured rats.

Yu W; Haoa JX; Xu XJ; Saydoff J; Sherman S; Eriksson A; Haegerstrand A; Wiesenfeld-Hallin Z
Article: CYTOKINE. 1997;9(12):1028-1033

Nociceptive responses in interleukin-6-deficient mice to peripheral inflammation and peripheral nerve section.

Xu XJ; Hao JX; Andell-Jonsson S; Poli V; Bartfai T; Wiesenfeld-Hallin Z
Article: NEUROSCIENCE LETTERS. 1997;235(3):154-156

The effect of naturally occurring fragments of galanin message-associated peptide on spinal cord excitability in rats.

Andell-Jonsson S; Xu IS; Bartfai T; Xu XJ; Wiesenfeld-Hallin Z
Article: BEHAVIORAL AND BRAIN SCIENCES. 1997;20(3):420-425

Central inhibitory dysfunctions: mechanisms and clinical implications.

Wiesenfeld-Hallin Z; Aldskogius H; Grant G; Hao JX; Hökfelt T; Xu XJ
Article: NEUROPEPTIDES. 1997;31(3):287-291

CI 988, an antagonist of the cholecystokinin-B receptor, potentiates endogenous opioid-mediated antinociception at spinal level.

Xu XJ; Elfvin A; Hao JX; Fournié-Zaluski MC; Roques BP; Wiesenfeld-Hallin Z
Article: BRAIN RESEARCH. 1997;756(1-2):141-146

The development of morphine tolerance and dependence in rats with chronic pain.

Yu W; Hao JX; Xu XJ; Wiesenfeld-Hallin Z
Article: BRAIN RESEARCH. 1997;752(1-2):52-60

Effects of the capsaicin analogue resiniferatoxin on spinal nociceptive mechanisms in the rat: behavioral, electrophysiological and in situ hybridization studies.

Xu XJ; Farkas-Szallasi T; Lundberg JM; Hökfelt T; Wiesenfeld-Hallin Z; Szallasi A
Article: NEUROREPORT. 1997;8(5):1311-1316

Interferon-gamma receptors in nociceptive pathways: role in neuropathic pain-related behaviour.

Robertson B; Xu XJ; Hao JX; Wiesenfeld-Hallin Z; Mhlanga J; Grant G; Kristensson K
Article: NEUROSCIENCE LETTERS. 1997;223(1):49-52

Lack of cross-tolerance between the antinociceptive effect of intrathecal orphanin FQ and morphine in the rat.

Hao JX; Wiesenfeld-Hallin Z; Xu XJ
Article: EUROPEAN JOURNAL OF PAIN. 1997;1(1):17-29

Comparison of the anti-allodynic and antinociceptive effects of systemic; intrathecal and intracerebroventricular morphine in a rat model of central neuropathic pain.

Yu W; Hao JX; Xu XJ; Wiesenfeld-Hallin Z
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1996;318(2-3):301-306

Fragments of galanin message-associated peptide (GMAP) modulate the spinal flexor reflex in rat.

Xu XJ; Andell S; Bartfai T; Wiesenfeld-Hallin Z
Article: BRAIN RESEARCH. 1996;739(1-2):263-275

Spinal NK1 receptors contribute to the increased excitability of the nociceptive flexor reflex during persistent peripheral inflammation.

Parsons AM; Honda CN; Jia YP; Budai D; Xu XJ; Wiesenfeld-Hallin Z; Seybold VS
Article: ACTA PHYSIOLOGICA. 1996;158(3):269-273

N-methyl-D-aspartate receptor antagonists potentiate morphine's antinociceptive effect in the rat.

Grass S; Hoffmann O; Xu XJ; Wiesenfeld-Hallin Z
Article: BRAIN RESEARCH. 1996;736(1-2):28-34

Effects of intrathecal vs. systemic clonidine in treating chronic allodynia-like response in spinally injured rats.

Hao JX; Yu W; Xu XJ; Wiesenfeld-Hallin Z
Article: NEUROREPORT. 1996;7(13):2092-2094

Nociceptin or antinociceptin: potent spinal antinociceptive effect of orphanin FQ/nociceptin in the rat.

Xu XJ; Hao JX; Wiesenfeld-Hallin Z
Article: PAIN. 1996;66(2-3):313-319

Treatment of a chronic allodynia-like response in spinally injured rats: effects of systemically administered nitric oxide synthase inhibitors.

Hao JX; Xu XJ
Article: BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY. 1996;79(1):40-46

Disposition and analgesic effects of systemic morphine, morphine-6-glucuronide and normorphine in rat.

Hasselström J; Svensson JO; Säwe J; Wiesenfeld-Hallin Z; Yue QY; Xu XJ
Article: NEUROSCIENCE LETTERS. 1996;211(1):65-67

Sciatic nerve section induces mechanical hyperalgesia in skin adjacent to the deafferented region in rats: lack of correlation with autotomy behavior.

Kauppila T; Xu XJ
Article: NEUROSCIENCE. 1996;72(3):801-804

Intrathecal pituitary adenylate cyclase activating polypeptide facilitates the spinal nociceptive flexor reflex in the rat.

Xu XJ; Wiesenfeld-Hallin Z
Article: BRAIN RESEARCH. 1996;722(1-2):177-180

Capsaicin-sensitive afferents mediate chronic cold, but not mechanical, allodynia-like behavior in spinally injured rats.

Hao JX; Yu W; Xu XJ; Wiesenfeld-Hallin Z
Article: NEUROPEPTIDES. 1996;30(2):203-206

L-740,093, a new antagonist of the CCK-B receptor, potentiates the antinociceptive effect of morphine: electrophysiological and behavioural studies.

Xu XJ; Hoffmann O; Wiesenfeld-Hallin Z
Article: NEUROSCIENCE LETTERS. 1996;204(3):185-188

Calcitonin gene-related peptide (8-37) does not antagonize calcitonin gene-related peptide in rat spinal cord.

Xu XJ; Wiesenfeld-Hallin Z
Article: BRITISH JOURNAL OF PHARMACOLOGY. 1995;116(3):2076-2080

New high affinity peptide antagonists to the spinal galanin receptor.

Xu XJ; Wiesenfeld-Hallin Z; Langel U; Bedecs K; Bartfai T
Article: NEUROSCIENCE LETTERS. 1995;196(1-2):116-118

Subcutaneous carrageenan, but not formalin, increases the excitability of the nociceptive flexor reflex in the rat.

Xu XJ; Elfvin A; Wiesenfeld-Hallin Z
Article: REGULATORY PEPTIDES. 1995;58(1-2):19-24

The effects of intrathecal galanin message-associated peptide (GMAP) on the flexor reflex in rats.

Xu XJ; Andell S; Hao JX; Wiesenfeld-Hallin Z; Bartfai T
Article: NEUROPEPTIDES. 1995;28(5):299-307

Peripheral axotomy increases the expression of galanin message-associated peptide (GMAP) in dorsal root ganglion cells and alters the effects of intrathecal GMAP on the flexor reflex in the rat.

Xu XJ; Andell S; Zhang X; Wiesenfeld-Hallin Z; Langel U; Bedecs K; Hökfelt T; Bartfai T
Article: EUROPEAN JOURNAL OF PHARMACOLOGY. 1995;272(2-3):219-222

Intrathecal alpha-trinositol facilitates the flexor reflex but does not block the depressive effect of neuropeptide Y.

Xu XJ; Wiesenfeld-Hallin Z
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Review: EXPERIENTIA SUPPLEMENTUM. 2010;102:39-50

Galanin and spinal pain mechanisms: past, present, and future.

Xu X-J; Hökfelt T; Wiesenfeld-Hallin Z
Review: CELLULAR AND MOLECULAR LIFE SCIENCES. 2008;65(12):1813-1819

Galanin and spinal pain mechanisms: where do we stand in 2008?

Xu X-J; Hökfelt T; Wiesenfeld-Hallin Z
Published paper: NEUROPEPTIDES. 2005;39(3):207-210

Galanin and spinal nociceptive mechanisms: recent results from transgenic and knock-out models.

Wiesenfeld-Hallin Z; Xu X-J; Crawley JN; Hökfelt T
Review: TRENDS IN PHARMACOLOGICAL SCIENCES. 2003;24(12):634-639

Opioid hyperalgesia and tolerance versus 5-HT1A receptor-mediated inverse tolerance.

Xu X-J; Colpaert F; Wiesenfeld-Hallin Z
Published paper: DRUG DEVELOPMENT RESEARCH. 2003;58(4):350-353

Consequences of eliminating adenosine A₁ receptors in mice

Fredholm BB; Halldner L; Johansson C; Schulte G; Lövdahl C; Thorén P; Dunwiddie TV; Masino SA; Poelchen W; Diao LH; Illes P; Zahniser NR; Valen G; Tokuno S; Sommerschild H; Giménez-Llort L; Fernández-Teruel A; Escorihuela RM; Wiesenfeld-Hallin Z; Xu XJ; Hårdemark A; Herlenius E; Pekny S; Gebré-Medhin S; Brown R; Ollerstam A; Persson AEG; Skott O; Johansson B
Published paper: EUROPEAN JOURNAL OF PHARMACOLOGY. 2001;429(1-3):49-59

Neuropeptides in neuropathic and inflammatory pain with special emphasis on cholecystokinin and galanin.

Wiesenfeld-Hallin Z; Xu XJ
Review: NEUROPEPTIDES. 2000;34(3-4):137-147

Galanin and spinal nociceptive mechanisms: recent advances and therapeutic implications.

Xu XJ; Hökfelt T; Bartfai T; Wiesenfeld-Hallin Z
Published paper: BRAIN RESEARCH. 1999;848(1-2):78-89

Cholecystokinin/opioid interactions.

Wiesenfeld-Hallin Z; de Araúja Lucas G; Alster P; Xu XJ; Hökfelt T
Published paper: ANNALS OF THE NEW YORK ACADEMY OF SCIENCES. 1998;863:383-389

Galanin in somatosensory function.

Wiesenfeld-Hallin Z; Xu XJ
Review: ACTA ANAESTHESIOLOGICA SCANDINAVICA, SUPPLEMENT. 1997;110:127-128

Mechanisms of central pain.

Xu XJ; Hao JX; Kupers R; Yu W; Wiesenfeld-Hallin Z
Review: REGULATORY PEPTIDES. 1996;65(1):23-28

The role of cholecystokinin in nociception, neuropathic pain and opiate tolerance.

Wiesenfeld-Hallin Z; Xu XJ
Review: NEUROSCIENCE FOR ADDICTION MEDICINE: FROM PREVENTION TO REHABILITATION - CONSTRUCTS AND DRUGS. 1996;110:113-124

Plasticity of messenger function in primary afferents following nerve injury--implications for neuropathic pain.

Wiesenfeld-Hallin Z; Xu XJ
Review: NEUROSCIENCE. 1995;64(4):893-915

Ultrastructural studies on peptides in the dorsal horn of the rat spinal cord--III. Effects of peripheral axotomy with special reference to galanin.

Zhang X; Bean AJ; Wiesenfeld-Hallin Z; Xu XJ; Hökfelt T
Other: BRAIN RESEARCH. 1995;670(2):342-346

Plasticity in spinal nociception after peripheral nerve section: reduced effectiveness of the NMDA receptor antagonist MK-801 in blocking wind-up and central sensitization of the flexor reflex.

Xu XJ; Zhang X; Hökfelt T; Wiesenfeld-Hallin Z

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Affiliated to Research, Department of Laboratory Medicine, Karolinska Institutet, 2024-2026
Affiliated to Research, Department of Physiology and Pharmacology, Karolinska Institutet, 2022-2024

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Docent, Karolinska Institutet, 2000

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