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Yasmin Yu

PhD Student

We are investigating autophagy and the lipid kinase VPS34 as targets in anti-cancer therapy.
It is a joint project between the Pokrovskaja Tamm group at OnkPat and the company Sprint Bioscience.

Research description

Inhibition of Vps34 reprograms cold into hot inflamed tumors and improves anti-PD-1/PD-L1 immunotherapy. Noman MZ, Parpal S, Van Moer K, Xiao M, Yu Y, Viklund J, De Milito A, Hasmim M, Andersson M, Amaravadi RK, Martinsson J, Berchem G, Janji B Sci Adv 2020 May;6(18):eaax7881

Targeting autophagy by small molecule inhibitors of vacuolar protein sorting 34 (Vps34) improves the sensitivity of breast cancer cells to Sunitinib. Dyczynski M, Yu Y, Otrocka M, Parpal S, Braga T, Henley AB, Zazzi H, Lerner M, Wennerberg K, Viklund J, Martinsson J, Grandér D, De Milito A, Pokrovskaja Tamm K Cancer Lett 2018 10;435():32-43

Identification of novel small molecules that inhibit STAT3-dependent transcription and function. Kolosenko I, Yu Y, Busker S, Dyczynski M, Liu J, Haraldsson M, Palm Apergi C, Helleday T, Tamm KP, Page BDG, Grander D PLoS One 2017 ;12(6):e0178844

Education

2014 - 2016     Master of Science (M.Sc.) in Biomedicine, Karolinska Institutet

2011 - 2014     Bachelor of Science (B.Sc.) in Bioscience, Ruprecht-Karls-Universität Heidelberg

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