Research description
I am a PhD student in Ingrid Kockum's research group, mainly under Xia Jiang's supervision. In my PhD project, I bend my efforts to genetic epidemiology. The title of my research project is "Using larger-scale genetic data and complied analytical strategy to understand the etiology and sex disparity of multiple sclerosis". I use extensive genetic information, as well as publicly available Genome-Wide Association Study summary statistics on modifiable environmental exposures, to assess a putative causal relationship and shared genetic component between risk factors and multiple sclerosis (MS).
Currently, I'm mainly involved in the following projects:
- Understand the role of hormonal exposure and risk of multiple sclerosis - a population-based approach and a genome-wide cross-trait analysis (polycystic ovarian syndrome, sex hormones, and risk of MS)
- A genome-wide cross-trait analysis between modifiable lifestyle factors and multiple sclerosis (obesity and MS, body mass index, waist-to-hip ratio)
- A genome-wide cross-trait analysis between nutritional exposure and multiple sclerosis (vitamin D and MS)
- A genome-wide cross-trait analysis between multiple sclerosis and its neurological comorbidities (depression, anxiety, and MS)