About me
Associate Professor of Experimental Pathology, Karolinska Institutet
Head of Molecular Cancer Diagnostics (Molecular Pathology), Karolinska University Hospital Solna
M.D. / Ph.D., Consultant Clinical Pathologist
Research description
Precision Medicine, cancer genomics
Soft tissue and bone tumors, genomics and biology
Recent publications:
Sarcoma Tumor Microenvironment. Tsagozis P, Gonzalez-Molina J, Georgoudaki AM, Lehti K, Carlson J, Lundqvist A, Haglund F, Ehnman M.Adv Exp Med Biol. 2020;1296:319-348. doi: 10.1007/978-3-030-59038-3_20. PMID: 34185302
Identification of an RNA-Binding-Protein-Based Prognostic Model for Ewing Sarcoma. Chen Y, Su H, Su Y, Zhang Y, Lin Y, Haglund F. Cancers (Basel). 2021 Jul 25;13(15):3736. doi: 10.3390/cancers13153736. PMID: 34359637
Follicular Helper T-Cell-Based Classification of Endometrial Cancer Promotes Precise Checkpoint Immunotherapy and Provides Prognostic Stratification. Chen Y, You S, Li J, Zhang Y, Kokaraki G, Epstein E, Carlson J, Huang WK, Haglund F. Front Immunol. 2022 Jan 7;12:788959. doi: 10.3389/fimmu.2021.788959. eCollection 2021 PMID: 35069566
Identification of an RNA-Binding-Protein-Based Prognostic Model for Ewing Sarcoma. Chen Y, Su H, Su Y, Zhang Y, Lin Y, Haglund F. Cancers (Basel). 2021 Jul 25;13(15):3736. doi: 10.3390/cancers13153736.PMID: 34359637 Free PMC article.
TERT promoter mutation is an objective clinical marker for disease progression in chondrosarcoma. Zhang Y, Chen Y, Yang C, Seger N, Hesla AC, Tsagkozis P, Larsson O, Lin Y, Haglund F. Mod Pathol. 2021 Nov;34(11):2020-2027. doi: 10.1038/s41379-021-00848-0. Epub 2021 Jun 9. PMID: 34108637
CD11c-CD8 Spatial Cross Presentation: A Novel Approach to Link Immune Surveillance and Patient Survival in Soft Tissue Sarcoma. Su Y, Tsagkozis P, Papakonstantinou A, Tobin NP, Gultekin O, Malmerfelt A, Ingelshed K, Neo SY, Lundquist J, Chaabane W, Nisancioglu MH, Leiss LW, Östman A, Bergh J, Sedimbi S, Lehti K, Lundqvist A, Stragliotto CL, Haglund F, Ehnman M.Cancers (Basel). 2021 Mar 9;13(5):1175. doi: 10.3390/cancers13051175.PMID: 33803245
Clear-cell chondrosarcomas: Fine-needle aspiration cytology, radiological findings, and patient demographics of a rare entity. Zhang Y, Alagic Z, Tani E, Skorpil M, Tsagkozis P, Haglund F.Diagn Cytopathol. 2021 Jan;49(1):46-53. doi: 10.1002/dc.24582. Epub 2020 Aug 12.PMID: 32786062
Nuclear IGF1R interact with PCNA to preserve DNA replication after DNA-damage in a variety of human cancers. Yang C, Zhang Y, Chen Y, Ragaller F, Liu M, Corvigno S, Dahlstrand H, Carlson J, Chen Z, Näsman A, Waraky A, Lin Y, Larsson O, Haglund F.PLoS One. 2020 Jul 23;15(7):e0236291. doi: 10.1371/journal.pone.0236291. eCollection 2020.PMID: 32701997
Transcriptome profiling of Ewing sarcomas - treatment resistance pathways and IGF-dependency. Chen Y, Hesla AC, Lin Y, Ghaderi M, Liu M, Yang C, Zhang Y, Tsagkozis P, Larsson O, Haglund F.Mol Oncol. 2020 May;14(5):1101-1117. doi: 10.1002/1878-0261.12655. Epub 2020 Mar 13.PMID: 32115849
Education
MD, Karolinska Institutet 2012
PhD, Karolinska Institutet 2013
Licenced physician 2014
Associate Progessor of Experimental Pathology, Karolinska Institutet 2019
Consultant Clinical Pathologist 2019
Academic honours, awards and prizes
Thesis of the Year, Swedish Association of Pathology 2014
Young Researcher Award, Euro Ewing Consortium 2018