Portrait

Hassan Gharibi

Postdoctoral researcher

About me

I am a Postdoctoral Fellow in Roman Zubarev's group (Chemical Proteomics Core Facility) in the Department of Medical Biochemistry and Biophysics at Karolinska Institutet, Sweden.

Research description

My project is focused on developing a high-resolution Orbitrap-based mass spectrometry method (FT IsoR MS) to simultaneously acquire isotopic ratio of C, H, N, and O elements in individual amino acids alongside protein sequencing and profiling with only a microgram amount of sample.

 

Selected Publication:

1. Gharibi. H et al. 2022Abnormal (Hydroxy)proline Deuterium Content Redefines Hydrogen Chemical Mass. Journal of American Chemical Society, 144, 6.

2. Gharibi. H et al. 2022Proteomics-Compatible Fourier Transform Isotopic Ratio Mass Spectrometry of PolypeptidesAnalytical Chemistry, 94 (43), 15048-15056.

3. Gharibi. H et al. 2022Measurements of heterogeneity in proteomics analysis of the nanoparticle protein corona across core facilitiesNature Communication 13, 6610

4. Zhang. X, Meng. Z, Gharibi. H et al. 2023. Ultralight Ultrafast Enzymes. Angewandte Chemie. doi:10.1002/anie.202316488

5. Kurth. M, Barayeu. U, Gharibi. H et al. 2023. DOPA Residues Endow Collagen with Radical Scavenging CapacityAngewandte Chemie. e202216610.

6. Gharibi. H et al. 2023. Massive Solubility Changes in Neuronal Proteins upon Simulated Traumatic Brain Injury Reveal the Role of Shockwaves in Irreversible Damage. Molecules 2023 Sep;28(19).

7. Gharibi. H et al. 2022Multi-omics analysis of magnetically levitated plasma biomoleculesBiosensors and Bioelectronics, 114862.

8. Saei. A, Beusch. C, Sabatier. P, Astorga Wells. J, Gharibi. H et al. 2021System-wide Identification and prioritization of Enzyme Substrates by Thermal Analysis (SIESTA). Nature Communications 12, 1296 

Teaching portfolio

Lab Teacher Assistant for General and Organic Chemistry (2021HT, 2022HT, 2023HT)

Education

2018 - 2023: PhD in Medical Science, Karolinska Institutet, Sweden

2015 - 2018: MSc in Biotechnology Engineering, Tarbiat Modares University, Iran

2009 - 2015: BSc in Chemical Engineering, Sharif University of Technology, Iran