About me

Professor of Molecular Physiology and group leader for the Molecular and Cellular Exercise Physiology research group. 

Jorge Ruas received his Pharm.D. degree from the University of Lisbon, Portugal, after which he initiated pre-doctoral work at Karolinska Institutet. During his doctoral studies he investigated how cellular oxygen levels can regulate gene expression, and in 2005 received his Ph.D. in Cell and Molecular Biology.

In 2006 he moved to Boston to pursue postdoctoral studies at the Division of Metabolism and Chronic Disease at the Dana-Farber Cancer Institute and Harvard Medical School. During this period he focused on the study of transcriptional networks that control skeletal muscle physiology.

Dr. Ruas set up his laboratory at the Department of Physiology and Pharmacology at Karolinska Institutet in July 2011. In 2016 he became Associate Professor, and in 2020 Professor of Molecular Physiology. His research group studies the molecular physiology of physical exercise and how to use this knowledge to develop novel therapies.

Research description

Research in our laboratory is aimed at understanding the molecular mechanisms that mediate skeletal muscle adaptations to diverse challenges and their local and systemic consequences. We are particularly interested in understanding how exercised or sedentary skeletal muscle can crosstalk with other organs, and how it can affect individual health and disease.

Academic honours, awards and prizes

2019 Novo Nordisk Foundation Ascending Investigator, Endocrinology and Metabolism

2017 The Leif C. Groop Award for Outstanding Diabetes Research

2016 Swedish Research Council Consolidator Grant

2015 Senior Researcher Award from Karolinska Institutet

2014 Human Frontier Science Program Young Investigator Award

2013 Malin and Lennart Philipson Prize (link to ki.se/news) 

Jorge Ruas - award winner 2013-2015 (link to Malin and Lennart Philipson's foundation website)

2012 Novo Nordisk Fonden Excellence Project Award

2012 Marie Curie Career Integration Grant

2011 Assistant Professor Grant from the Swedish Research Council

2011 Young Investigator Award in Diabetes. Strategic Research Programme in Diabetes at Karolinska Institutet (Sweden).

2006 Wenner Gren Fellow