My main research interest is in the field of pharmacoepidemiology. My current projects include studies of the risks and benefits of psychotropic medications (e.g., antidepressants, ADHD medication) using large-scale population data (e.g., national health registers, medical claim database).
As a separate research interest, I've also participated in a series of studies on the associations between mental and somatic disorders, using various data sources from Sweden, China, and the US.
Risks and Benefits of Attention-Deficit/Hyperactivity Disorder Medication on Behavioral and Neuropsychiatric Outcomes: A Qualitative Review of Pharmacoepidemiology Studies Using Linked Prescription Databases. Chang Z, Ghirardi L, Quinn PD, Asherson P, D'Onofrio BM, Larsson H Biol. Psychiatry 2019 Sep;86(5):335-343
Association Between Prescription of Major Psychotropic Medications and Violent Reoffending After Prison Release. Chang Z, Lichtenstein P, Långström N, Larsson H, Fazel S JAMA 2016 Nov;316(17):1798-1807
Medication for Attention-Deficit/Hyperactivity Disorder and Risk for Depression: A Nationwide Longitudinal Cohort Study. Chang Z, D'Onofrio BM, Quinn PD, Lichtenstein P, Larsson H Biol. Psychiatry 2016 12;80(12):916-922
Substance use disorders, psychiatric disorders, and mortality after release from prison: a nationwide longitudinal cohort study. Chang Z, Lichtenstein P, Larsson H, Fazel S Lancet Psychiatry 2015 May;2(5):422-430
Serious transport accidents in adults with attention-deficit/hyperactivity disorder and the effect of medication: a population-based study. Chang Z, Lichtenstein P, D'Onofrio BM, Sjölander A, Larsson H JAMA Psychiatry 2014 Mar;71(3):319-25
Current doctoral students
Current research grants
I have received funding from the Swedish Research Council (VR), Swedish Research Council for Health, Working Life, and Welfare (Forte), Norwegian research counsel, Karolinska Institutet Research Foundation and Thurings Stiftelse.
- PhD in Epidemiology, Karolinska Institutet, 2013
- MSc in Biomedicine, Karolinska Institutet, 2009
- BSc in Life Science, Fudan University, 2007
Academic honours, awards and prizes
- Rafaelsen Young Investigator Award from the International College of Neuropsychopharmacology, 2019
- COFAS Marie Curie International Postdoc Fellowship, 2014