Apple Tay

About me

Immunosuppression in the solid tumor microenvironment
- Adenosine signaling axis
- Pseudohypoxia in ccRCC
- Myeloid cell compartment in PDAC
- Secretome of Tumor-Myeloid 3D model

Article: CANCER RESEARCH. 2023;83(10):1628-1645

FPR2 Shapes an Immune-Excluded Pancreatic Tumor Microenvironment and Drives T-cell Exhaustion in a Sex-Dependent Manner.

He F; Tay AHM; Calandigary A; Malki E; Suzuki S; Liu T; Wang Q; Fernández-Moro C; Kaisso M; Olofsson-Sahl P; Melssen M; Sze SK; Björnstedt M; Löhr MJ; Karlsson MCI; Heuchel R; Sarhan D
Article: PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023;120(1):e2209856120

Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction.

Chen X; Sifakis EG; Robertson S; Neo SY; Jun S-H; Tong L; Hui Min AT; Lövrot J; Hellgren R; Margolin S; Bergh J; Foukakis T; Lagergren J; Lundqvist A; Ma R; Hartman J
Article: FRONTIERS IN IMMUNOLOGY. 2023;14:1264012

Inhibition of ERO1a and IDO1 improves dendritic cell infiltration into pancreatic ductal adenocarcinoma.

Tay AHM; Cinotti R; Sze NSK; Lundqvist A
Article: JOURNAL FOR IMMUNOTHERAPY OF CANCER. 2022;10(5):e004592

A2B adenosine receptor antagonists rescue lymphocyte activity in adenosine-producing patient-derived cancer models.

Tay AHM; Prieto-Díaz R; Neo S; Tong L; Chen X; Carannante V; Önfelt B; Hartman J; Haglund F; Majellaro M; Azuaje J; Garcia-Mera X; Brea JM; Loza MI; Jespers W; Gutierrez-de-Teran H; Sotelo E; Lundqvist A

Thesis / dissertation: 2023

Art of tumor immunity : extricating hypoxia-driven immunosuppression in the solid tumor microenvironment

Tay, Apple
Conference publication: CANCER RESEARCH. 2023;83(7):4466

Inhibition of ERO1a and IDO1 improves dendritic cell infiltration into pancreatic ductal adenocarcinoma

Tay A; Lundqvist A; Sze SK
Review: MOLECULAR CANCER. 2022;21(1):206

NK cells and solid tumors: therapeutic potential and persisting obstacles.

Tong L; Jiménez-Cortegana C; Tay AHM; Wickström S; Galluzzi L; Lundqvist A
Meeting abstract: ANNALS OF ONCOLOGY. 2022;33(7):S1306

Breast cancer patient-derived whole-tumor cell culture model for efficient drug profiling and treatment response prediction

Chen X; Sifakis EG; Robertson S; Neo SY; Jun S-H; Tong L; Lovrot J; Tay A; Hellgren R; Margolin S; Bergh J; Foukakis T; Lagergren J; Lundqvist A; Ma R; Hartman J