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Our research focuses on various mechanistic aspects of the DDR and DNA repair pathways. Of particular interest is discovery of targets and markers for personalized cancer treatment and finding novel components or mechanisms of genome integrity maintenance. Another of our long-term goals is to further unravel the principles of ribosome biogenesis surveillance and to understand the dynamics and the finer details of the p53 pathway in sensing ribosome dysfunction, and how ribosomal stress crosstalk with the DNA damage response.

Jiri Bartek

Professor

Our research focuses on various mechanistic aspects of the DDR and DNA repair pathways. Of particular interest is discovery of targets and markers for personalized cancer treatment and finding novel components or mechanisms of genome integrity maintenance. Another of our long-term goals is to further unravel the principles of ribosome biogenesis surveillance and to understand the dynamics and the finer details of the p53 pathway in sensing ribosome dysfunction, and how ribosomal stress crosstalk with the DNA damage response.

Education

1983: Ph.D. degree at the Inst. Molec. Genetics, Czech Acad. Sci., Prague, Czech Republic

1979: M.D. degree at the Medical Faculty, Palacky University, Olomouc, Czech Republic

Academic honours, awards and prizes

2016: Fernströmstiftelsens Stora nordiska pris

2013: Silver Medal of Merits from the Senate of the Czech Republic

2012: Elected member of the Danish Royal Academy of Sciences and Arts

2009: Shai-Shacknai Prize for Cancer Research, University of Jerusalem, Israel

2009: Founding member: European Academy of Cancer Sciences

2005: Doctor Honoris Causa, Palacky University, Olomouc, Czech Republic

2003: G. J. Mendel Honorary Medal for Merit in the Biological Sciences

2003: Novo Nordisk Prize, Denmark

2002: Alfred Benzons Prize, Denmark

2002: Honorary Professor, The Faculty of Health Sciences, University of Aarhus

2002: Honorary Professor, The Faculty of Health Sciences, University of Copenhagen

2000: Elected member of the European Molecular Biology Organization – EMBO

1998: The Prize of the Danish Association for Cancer Research

1988: J.E. Purkyne Prize for medical sciences

 

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