Jonas Spaak

Jonas Spaak

Affiliated to research

About me

Jonas Spaak, Associate Professor (Docent) in Cardiology, consultant in heart failure and hypertension. Department of Cardiology, Danderyd University Hospital and Department of Clinical Sciences, Danderyd University Hospital, Karolinska Institutet

Research description

Cardiovascular disease with concomitant kidney disease and diabetes: from vascular dysfunction to integrated complex chronic disease management

My current research focus on the Cardiorenal Syndrome and I have instigated the Karolinska Cardiorenal Theme Centre (KKT) with its associated biobank Stockholmheartbank. In this area I am main supervisor for 5 PhD students trying to better understand vascular dysfunction and associated disturbances in patients with reduced kidney function.

Second; I am clinically head for a unique multiprofessional integrated clinic for patients with concomitant cardiovascular disease, renal failure and diabetes (HND-centrum). At this clinic I conduct the randomised trial CareHND, which will give new insight into chronic complex disease management from several perspectives.


Research group

-Main supervisor for PhD student and Nephrologist Josefin Mörtberg on “Hemostasis, Renal insufficiency and Cardiovascular disease”.

-Main supervisor for PhD student and MD Hermine Rietz on “Cardiovascular effects of obstructive sleep apnea”.

-Main supervisor for PhD student and MD Kristina Lundwall on “Vascular function, vitamin D deficiency and hyperphosphatemia in chronic kidney disease”.

-Main supervisor for PhD student and Cardiologist Christina Ekenbäck on “Sympathetic and vascular regulation in myocardial infarction with angiographically normal coronary arteries”.

-Main supervisor for PhD student and MD Masih Khedri on “Renal dysfunction and long term outcome after myocardial infarction”.

-Co-supervisor for PhD student Liyew Desta, Cardiologist, on "Post-infarction Heart failure in Acute Coronary Syndromes – Patterns and determinants of prognosis in the SWEDEHEART/RIKS-HIA registry".

-Co-supervisor for PhD student Gudrun Evén, RN, on "Patients' perception of care and measures of safety in a multidiciplinary person-centered clinic".

-Co-supervisor for PhD Student George Keel, MA, on "What is the value of multidisciplinary collaboration in healthcare? -Outcomes and costs of a person-centered integrated care unit for patients with cardiovascular disease, renal dysfunction and diabetes".

-Co-supervisor for PhD Student Muhammad Rafiq, MA. "Eliminating guesswork: An exploration of the role of predictive modelling in care management for patients with multimorbidities".

-Co-supervisor for PhD Student Helge Brandberg, MD. "Computerized, patient-entered medical histories to improve the management of acute chest pain patients".

Teaching portfolio

500+ hours teaching at the MD program, Karolinska Instiututet.

50+ invited lectures.


MD, Karolinska Institutet, 1999

PhD, Karolinska Institutet, 2001

Clinical Research Fellowship (post-doctoral), Mount Sinai Hospital and University of Toronto, Cardiology, 2001-2004.

Visiting Scientist, Prince of Wales Medical Research Institute, Sydney, 3 months, 2002.

Specialist in Internal Medicine, 2011

Specialist in Cardiology, 2013

Academic honours, awards and prizes

- Sir Stanley Davidson Lecturer, Royal College of Physicians of Edinburgh, 2016.

- Chair of Steering-committee of KIRCNET; Karolinska Respiration and Circulation research NETwork (

- Scientific Secretary in Swedish Vascular Medicine Society (

- Swedish representative in VAS, Vascular Independent Research and Education European Organisation.

- Swedish representative in European Union Medical Specialists, div. Angiology and vascular medicine.

- Member of the departmental PhD admittance board and Research Board.

- Scientific Secretary in Swedish Working Group for Renal Denervation.

Loading bibliometrics...