Marco Gerling

Marco Gerling

Researcher

Department and organisational affiliation:

About me

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I am group leader at the Department of Biosciences and Nutrition at Karolinska Institutet. I work 50% as clinician in oncology at Karolinska University Hospital, Tema Cancer.

I graduated in 2008 from Lübeck University, Germany, as fully licensed physician. I received my doctoral degree in 2011, for which I did research as a guest student in Thomas Ried's lab at the NIH in Bethesda, USA. From 2009-2012, I worked clinically at the Charité, Berlin's university hospital, affiliated to Britta Siegmund's laboratory with an interest in colitis and colitis-associated colon cancer.

Cancerfonden funded me as a postdoc (2015-2018).

From Svenska Sällskapet för Medicinsk Forskning and Vetenskapsrådet, I have received funding to develop my own line of research in combination with 50% clinical work 2018-2022 (SSMF:s Stora Anslag, VR:s anställning till forskare på halvtid i klinisk miljö).

Additional support: Ruth och Richard Julins stiftelse, Åke Wiberg stiftelse, Jeanssons stiftelse, KI fonder, SLS, KID

Research description

My research centers around the role of non-cancer cells in liver metastases. 

Interactions with non-cancerous cell in the tumor microenvironment modify tumor cell behaviour, such as proliferation and differentiation. Clinically, the nature of these contacts influences prognosis and can be used to predict treatment response.

With my research, I want to understand the intricate mechanisms of intercellular communication between tumor cells. The main goals of our lab are to identify predictive and prognostic stromal markers, and to contribute to the development of novel, stroma-based therapies. 

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