Marcel Tarbier

About me
Publications
Public outreach and news

Research

Non-genetic single-cell heterogeneity
We are exploring mechanisms by which individual cells of otherwise
homogeneous populations achieve molecular heterogeneity and how this
heterogeneity affects their molecular behaviour i.e. to better understand why
certain cancer cells develop to become persister cells that are resistant to
treatment. For this we develop and apply novel single-cell approaches and
integrate data from various omics technologies.

Articles

Article: NATURE COMMUNICATIONS. 2024;15(1):2744

Gene-expression memory-based prediction of cell lineages from scRNA-seq datasets.

Eisele AS; Tarbier M; Dormann AA; Pelechano V; Suter DM
Article: MOLECULAR GENETICS AND GENOMICS. 2022;297(2):463-484

The SWI/SNF subunit BRG1 affects alternative splicing by changing RNA binding factor interactions with nascent RNA.

Gañez-Zapater A; Mackowiak SD; Guo Y; Tarbier M; Jordán-Pla A; Friedländer MR; Visa N; Östlund Farrants A-K
Article: NUCLEIC ACIDS RESEARCH. 2022;50(D1):D204-D210

MirGeneDB 2.1: toward a complete sampling of all major animal phyla.

Fromm B; Høye E; Domanska D; Zhong X; Aparicio-Puerta E; Ovchinnikov V; Umu SU; Chabot PJ; Kang W; Aslanzadeh M; Tarbier M; Mármol-Sánchez E; Urgese G; Johansen M; Hovig E; Hackenberg M; Friedländer MR; Peterson KJ
Article: COMMUNICATIONS BIOLOGY. 2021;4(1):624

A combined approach for single-cell mRNA and intracellular protein expression analysis.

Reimegård J; Tarbier M; Danielsson M; Schuster J; Baskaran S; Panagiotou S; Dahl N; Friedländer MR; Gallant CJ
Article: RNA. 2020;27(3):rna.078410.120-334

Ancient microRNA profiles of a 14,300-year-old canid samples confirm taxonomic origin and give glimpses into tissue-specific gene regulation from the Pleistocene.

Fromm B; Tarbier M; Smith O; Marmol-Sanchez E; Dalen L; Gilbert TP; Friedlander MR
Article: CELL REPORTS. 2020;33(10):108448

Circulating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development.

Malkani S; Chin CR; Cekanaviciute E; Mortreux M; Okinula H; Tarbier M; Schreurs A-S; Shirazi-Fard Y; Tahimic CGT; Rodriguez DN; Sexton BS; Butler D; Verma A; Bezdan D; Durmaz C; MacKay M; Melnick A; Meydan C; Li S; Garrett-Bakelman F; Fromm B; Afshinnekoo E; Langhorst BW; Dimalanta ET; Cheng-Campbell M; Blaber E; Schisler JC; Vanderburg C; Friedländer MR; McDonald JT; Costes SV; Rutkove S; Grabham P; Mason CE; Beheshti A
Article: NATURE COMMUNICATIONS. 2020;11(1):5445

Nuclear gene proximity and protein interactions shape transcript covariations in mammalian single cells.

Tarbier M; Mackowiak SD; Frade J; Catuara-Solarz S; Biryukova I; Gelali E; Menéndez DB; Zapata L; Ossowski S; Bienko M; Gallant CJ; Friedländer MR
Article: NUCLEIC ACIDS RESEARCH. 2018;46(22):11869-11882

Next-generation sequencing reveals two populations of damage-induced small RNAs at endogenous DNA double-strand breaks.

Bonath F; Domingo-Prim J; Tarbier M; Friedländer MR; Visa N
Article: MOLECULAR METABOLISM. 2018;18:15-24

Control of hepatic gluconeogenesis by Argonaute2.

Yan X; Wang Z; Bishop CA; Weitkunat K; Feng X; Tarbier M; Luo J; Friedländer MR; Burkhardt R; Klaus S; Willnow TE; Poy MN
Article: MOLECULAR METABOLISM. 2018;17:49-60

microRNA-205-5p is a modulator of insulin sensitivity that inhibits FOXO function.

Langlet F; Tarbier M; Haeusler RA; Camastra S; Ferrannini E; Friedländer MR; Accili D
Article: JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM. 2017;102(10):3749-3755

Differential Impact of Glucose Administered Intravenously and Orally on Circulating miR-375 Levels in Human Subjects.

Yan X; Wang Z; Westberg-Rasmussen S; Tarbier M; Rathjen T; Tattikota SG; Peck BCE; Kanke M; Oxvig C; Frystyk J; Starup-Linde J; Sethupathy P; Friedländer MR; Gregersen S; Poy MN

All other publications

Editorial comment: RNA. 2022;28(6):781-785

The limits of human microRNA annotation have been met.

Fromm B; Zhong X; Tarbier M; Friedländer MR; Hackenberg M

Research

Articles

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