Rafael Frias Beneyto

Publications
CV
Public outreach and news

Articles

Article: CANCER CHEMOTHERAPY AND PHARMACOLOGY. 2017;80(2):317-332

Chemotherapy-induced gastrointestinal toxicity is associated with changes in serum and urine metabolome and fecal microbiota in male Sprague-Dawley rats.

Forsgård RA; Marrachelli VG; Korpela K; Frias R; Collado MC; Korpela R; Monleon D; Spillmann T; Österlund P
Article: FOOD & FUNCTION. 2017;8(4):1622-1626

Mice exposed to infant formula enriched with polyamines: impact on host transcriptome and microbiome.

Gómez-Gallego C; García Romo M; Frías R; Periago MJ; Ros G; Salminen S; Collado MC
Article: AMINO ACIDS. 2017;49(3):529-540

Transglutaminase 2-specific coeliac disease autoantibodies induce morphological changes and signs of inflammation in the small-bowel mucosa of mice.

Kalliokoski S; Piqueras VO; Frías R; Sulic A-M; Määttä JAE; Kähkönen N; Viiri K; Huhtala H; Pasternack A; Laurila K; Sblattero D; Korponay-Szabó IR; Mäki M; Caja S; Kaukinen K; Lindfors K
Article: CANCER CHEMOTHERAPY AND PHARMACOLOGY. 2016;78(4):863-874

Intestinal permeability to iohexol as an in vivo marker of chemotherapy-induced gastrointestinal toxicity in Sprague-Dawley rats.

Forsgård RA; Korpela R; Holma R; Lindén J; Frias R; Spillmann T; Österlund P
Article: JOURNAL OF MOLECULAR MEDICINE-JMM. 2015;93(1):51-62

Injection of celiac disease patient sera or immunoglobulins to mice reproduces a condition mimicking early developing celiac disease.

Kalliokoski S; Caja S; Frias R; Laurila K; Koskinen O; Niemelä O; Mäki M; Kaukinen K; Korponay-Szabó IR; Lindfors K
Article: FOOD RESEARCH INTERNATIONAL. 2014;59:8-15

Polyamine supplementation in infant formula: Influence on lymphocyte populations and immune system-related gene expression in a Balb/cOlaHsd mouse model

Gomez-Gallego C; Frias R; Perez-Martinez G; Jose Bernal M; Jesus Periago M; Salminen S; Ros G; Carmen Collado M
Article: BRITISH JOURNAL OF NUTRITION. 2014;111(6):1050-1058

Resembling breast milk: influence of polyamine-supplemented formula on neonatal BALB/cOlaHsd mouse microbiota.

Gómez-Gallego C; Collado MC; Pérez G; Ilo T; Jaakkola U-M; Bernal MJ; Periago MJ; Frias R; Ros G; Salminen S
Article: SCANDINAVIAN JOURNAL OF LABORATORY ANIMAL SCIENCE. 2014;40(1):1-6

An in vivo permeability test protocol using iohexol to reduce and refine the use of laboratory rats in intestinal damage assessment

Frias R; Ouwehand AC; Jaakkold U-M; Spillmann T; Gueimonde M
Article: PLOS ONE. 2013;8(6):e65887

Celiac Disease-Specific TG2-Targeted Autoantibodies Inhibit Angiogenesis Ex Vivo and In Vivo in Mice by Interfering with Endothelial Cell Dynamics.

Kalliokoski S; Sulic A-M; Korponay-Szabó IR; Szondy Z; Frias R; Perez MA; Martucciello S; Roivainen A; Pelliniemi LJ; Esposito C; Griffin M; Sblattero D; Mäki M; Kaukinen K; Lindfors K; Caja S
Article: JOURNAL OF NUTRITIONAL BIOCHEMISTRY. 2012;23(11):1508-1513

Infant formula supplemented with polyamines alters the intestinal microbiota in neonatal BALB/cOlaHsd mice.

Gómez-Gallego C; Collado MC; Ilo T; Jaakkola U-M; Bernal MJ; Periago MJ; Salminen S; Ros G; Frias R
Article: AMERICAN JOURNAL OF VETERINARY RESEARCH. 2012;73(5):654-658

Urinary recovery of orally administered chromium 51-labeled EDTA, lactulose, rhamnose, d-xylose, 3-O-methyl-d-glucose, and sucrose in healthy adult male Beagles.

Frias R; Steiner JM; Williams DA; Sankari S; Westermarck E
Article: VETERINARY JOURNAL. 2012;192(1):123-125

Comparison of 51chromium-labeled ethylenediamine tetra-acetic acid and iohexol as blood markers for intestinal permeability testing in Beagle dogs.

Frias R; Strube K; Ternes W; Collado MC; Spillmann T; Sankari S; Westermarck E
Article: JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION. 2010;22(6):949-953

The 51-chromium-labeled ethylenediamine tetra-acetic acid intestinal permeability blood test in healthy Beagle dogs: a comparison between serum and plasma levels.

Frias R; Collado MC; Spillmann T; Sankari S; Westermarck E
Article: COMPARATIVE MEDICINE. 2010;60(5):369-373

Small intestinal permeability and serum folate and cobalamin absorption after surgical construction of permanent jejunal fistulas in laboratory beagle dogs.

Frias R; Harmoinen J; Laitinen-Vapaavuori O; Spillmann T; Sankari S; Westermarck E
Article: CHROMATOGRAPHIA. 2010;71(3-4):211-216

Rapid LC-UV Analysis of Iohexol in Canine Plasma for Glomerular Filtration Rate Determination

Poytakangas M; Saario-Paunio E; Putkonen T; Saastamoinen I; Frias R; Spillmann T; Saloniemi H
Article: FOOD RESEARCH INTERNATIONAL. 2009;42(5-6):636-640

Effect of clinical and probiotic Lactobacillus rhamnosus strains on intestinal permeability and bacterial translocation in healthy and colitic rats

Frias R; Ouwehand A; Spillmann T; Vankerckhoven V; Hewicker-Trautwein M; Salminen S; Gueimonde M
Article: JOURNAL OF VETERINARY INTERNAL MEDICINE. 2005;19(6):822-827

Effect of diet and tylosin on chronic diarrhea in beagles.

Westermarck E; Frias R; Skrzypczak T
Article: ANTIMICROBIAL AGENTS AND CHEMOTHERAPY. 2004;48(1):75-79

Orally administered targeted recombinant Beta-lactamase prevents ampicillin-induced selective pressure on the gut microbiota: a novel approach to reducing antimicrobial resistance.

Harmoinen J; Mentula S; Heikkilä M; van der Rest M; Rajala-Schultz PJ; Donskey CJ; Frias R; Koski P; Wickstrand N; Jousimies-Somer H; Westermarck E; Lindevall K

All other publications

Corrigendum: VETERINARY CLINICAL PATHOLOGY. 2010;39(1):128

Estimation of intestinal permeability in healthy dogs using the contrast medium iohexol (vol 38, pg 353, 2009)

Klenner S; Frias R; Coenen M; Failing K; Hewicker-Trautwein M; Ternes W; Verspohl J; Spillmann T
Published conference paper: BIOLOGIA. 2006;61(6):755-760

Assuring the continued safety of lactic acid bacteria used as probiotics

Gueimonde M; Frias R; Ouwehand AC
Published conference paper: JOURNAL OF VETERINARY INTERNAL MEDICINE. 2004;18(2):156-159

51Cr-EDTA absorption blood test: an easy method for assessing small intestinal permeability in dogs.

Frias R; Sankari S; Westermarck E

Employments

Affiliated to Research, Department of Laboratory Medicine, Karolinska Institutet, 2024-2027
Affiliated to Teaching/Tutoring, Comparative Medicine, Karolinska Institutet, 2023-2026

Degrees and Education

Docent, Karolinska Institutet, 2021

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