What you can/shall store in ELN

Here you can find examples on what you can/shall document in ELN
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Research documentation in ELN should be done in such a way that it is possible to follow and review the research process.

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What you SHALL document in ELN irrespective of the type of research you are performing:

Research documentation at KI and within KI ELN should be done in such a way that it is possible for co-workers and external peers to follow and review the research.

Research documentation within KI ELN should cover the intellectual and practical sides of research:

  • Background and Aim: What is your specific scientific question?
  • Data collection: Describe how you collect your data/which datasets you are working on
  • Processing and analysis of data: Include calculations and statistical analyses
  • Methods: Protocols, instructions, validation
  • Results: raw and processed data
KI ELN

Extra information/examples for experimental research:

Methods

  • laboratory apparatus used
  • Standards/controls used
  • Programs/scripts/statistical analysis used
  • Detailed experimental protocol

Materials

  • Antibodies, chemicals, buffers, solutions, kits: including lot/batch numbers, catalogue numbers, dilutions, etc
  • Sample species
  • Sample type: e.g. homogenate, biopsy, purified DNA

Data

  • Observational data: captured in real time, i.e. sensor readings
  • Experimental data: from lab equipment, i.e. chromatographs, blots, images, NGS data, flow cytometry files
  • Simulation data: generated by computer models
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Extra information/examples for epidemiological research:

Data and Metadata

  • Upload the final study population needed to run the statistical analyses
  • If data is not uploaded, provide a statement of where it is stored and who the contact person is
  • Upload any relevant metadata such as code books or variable lists

Analysis plan

  • Upload versions of the analysis plan
  • Upload study protocols

Programs and logfiles

  • Upload the statistical programs used to create the data
  • Upload descriptive analysis
  • Upload main results
  • Upload review programs
  • Attach output (log files, figures, tables)
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Extra information/examples for clinical research:

Investigator’s Brochure

  • List of abbreviations
  • Summary
  • Physical, chemical, pharmaceutical properties of medicinal products
  • Data from non-clinical studies
  • Data from clinical studies
  • References

 
Clinical study protocol

  • Introduction
  • Objectives
  • Study duration
  • Number of subjects
  • Informed consents
  • Subject selection criteria: inclusion/exclusion
  • Study plan
  • Protocols/Procedures
  • Endpoints definition
  • Safety Reporting
  • Adverse events
  • Management of dropouts

 
Study progress reports
 
Informed consent forms
 
Case report forms
 
Data information

  • Derived/compiled data, i.e from registries, databanks
  • Laboratory test readouts
  • Motor/non-motor test results
  • Information retrieved from medical records
  • Questionnaires
  • Interviews
KI ELN

What you CAN document in ELN irrespective of the type of research you are performing:

  • Ethical approvals: You can upload a copy of the signed ethical approval for the study as well as amendments (if applicable)
  • Meeting minutes: You can upload a copy of all meeting minutes with decisions clearly described
  • Contracts and agreements: You can upload a copy of Material Transfer Agreements, Data processing Agreements
  • Data management plans
  • Funding documents: You can upload a copy of grants applications, financial reports
  • Applications for access to material (e.g. registry data/biobank samples)
  • Project plans
  • Correspondence of principal importance
  • Publications: You can upload circulated manuscript versions, correspondence with the journal and final published version
  • Posters/Abstracts: You can upload underlying data, figures, correspondence and final version of the abstract